Table 1.

Baseline demographic and laboratory characteristics of HD patients stratified by serum bilirubin tertiles

ParametersSerum Bilirubin TertilesP
Lower (n = 221)Middle (n = 220)Upper (n = 220)
Age, years58.8 ± 13.958.8 ± 12.857.5 ± 13.40.469a
Male gender, n (%)114 (51.5)107 (48.6)114 (51.8)0.758b
Current smoker, n (%)76 (34.3)61 (27.7)74 (33.6)0.260b
Hypertension, n (%)131 (59.3)127 (57.7)120 (54.5)0.592b
Diabetes mellitus, n (%)72 (32.6)71 (32.3)63 (28.6)0.632b
Previous CV disease, n (%)65 (29.4)58 (26.3)73 (33.1)0.277b
HD duration, months75.3 ± 57.672.1 ± 60.773.4 ± 62.80.254a
Kt/V urea1.81 ± 0.441.85 ± 0.661.83 ± 0.480.735a
Cholesterol, mg/dl173 ± 38172 ± 35172 ± 370.993a
Triglyceride, mg/dl175 ± 111172 ± 112179 ± 1240.381a
HDL-cholesterol, mg/dl40 ± 1238 ± 1038 ± 120.877a
LDL-cholesterol, mg/dl113 ± 28112 ± 29110 ± 290.702a
Systolic BP, mmHg144 ± 22145 ± 29145 ± 220.851a
Diastolic BP, mmHg79 ± 1278 ± 1077 ± 110.727a
BMI, kg/m221.5 ± 2.822.0 ± 3.622.2 ± 2.90.065a
hsCRP, mg/L3.89 (1.03, 8.02)3.46 (0.95, 7.07)2.92 (0.73, 6.15)0.012c
Albumin, g/dl3.79 ± 0.363.95 ± 0.324.01 ± 0.32<0.001a
Hemoglobin, g/dl9.7 ± 1.010.3 ± 1.111.8 ± 1.0<0.001a
Dose of epoetin, U/kg per week69 ± 4168 ± 4070 ± 430.920a
Ferritin, μg/L393 (246, 737)396 (224, 638)307 (148, 478)<0.001c
Transferrin saturation, %32 ± 1433 ± 1633 ± 150.635a
Serum bilirubin, mg/dl0.59 ± 0.090.76 ± 0.040.99 ± 0.25<0.001a
  • Values in bold are statistically significant. Statistical analysis by aANOVA test,

  • b the Pearson χ2 test, and

  • c the Kruskal–Wallis test.