Table 2.

Baseline characteristics of patients with nonglomerular diseases by groups of GFR trajectory (inclusion between 2005 and 2009)

Baseline CharacteristicsSlow Decline (n=206)High Baseline eGFR/Moderate Decline (n=216)Low Baseline eGFR/Moderate Decline (n=183)Rapid Decline (n=8)
Age, median (IQR)10.0 (6.0–13.0)9.0 (5.5–13.0)12.0 (8.0–15.0)7.5 (3.0–12.0)
Female sex, n (%)81 (39)77 (36)51 (28)2 (25)
Race, n (%)
 White159 (77)157 (73)138 (75)5 (63)
 Black31 (15)46 (21)33 (18)3 (37)
 Other16 (8)13 (6)12 (7)0 (0)
Puberty, n (%)76 (37)60 (28)82 (45)2 (25)
Hypertension, n (%)94 (46)89 (41)79 (43)2 (25)
Diabetes, n (%)1 (1)1 (1)0 (0)0 (0)
History of febrile UTI, n (%)75 (36)73 (34)76 (42)6 (75)
Baseline GFR, median (IQR)50.3 (45.1–56.0)68.2 (58.5–79.7)30.3 (25.3–35.3)65.5 (54.4–95.6)
Urine protein-creatinine ratio, n (%)
 <0.589 (43)126 (58)25 (14)4 (50)
 0.5–225 (12)19 (9)46 (25)0 (0)
 ≥29 (5)12 (6)31 (17)1 (13)
Low serum albumin, n (%)3 (1)1 (0)9 (5)1(12)
High potassium (>5.2 mEq/L), n (%)14 (7)13 (6)17 (9)1 (13)
Acidosis (CO2<22 mEq/L), n (%)106 (51)99 (46)121 (66)3 (37)
High phosphate, n (%)15 (7)13 (6)42 (23)0 (0)
Uric acid, n (%)
 Low (<5.5)10 (5)53 (25)1 (1)4 (50)
 Moderate (5.5–7.5)26 (13)47 (22)1 (1)1 (13)
 High (>7.5)13 (6)11 (5)3 (2)0 (0)
Anemia, n (%)43 (21)26 (12)82 (45)4 (50)
  • Missing: puberty, n=35; hypertension, n=9; diabetes, n=4; history of febrile UTI, n=39; urinary protein-creatinine ratio, n=226; serum albumin, n=4; potassium, n=14; acidosis, n=4; phosphate, n=1; uric acid, n=473; anemia, n=19. IQR, interquartile range; UTI, urinary tract infection; CO2, carbon dioxide.