Table 2.

Prevention and management of hematopoietic stem cell transplant–associated AKI

Prevention and monitoring
 Optimization of fluid balance
 Careful use of nephrotoxic medication and contrast fluid
 Monitoring of kidney function
Treatment: general measures
 Optimization of fluid balance
 Discontinuation of nephrotoxic medications
 Aggressive treatment of underlying infections
Treatment: specific measures
 Marrow infusion syndrome: steroids
 Hepatic sinusoidal obstruction syndrome: albumin and terlipressin, defibrotide
 Thrombotic microangiopathy: treatment of hypertension, cessation of CNI, complement inhibition (?)
  • CNI, calcineurin inhibitor.