Table 2.

Clinical characteristics of patients with de novo intracranial aneurysm formation during follow-up

CharacteristicPatient No.
437106133162
Age at first MRA, yr5167294845
SexWWMWW
IA location on first MRABilateral MCAR ACAR MCAR SCABA
Time to detection of de novo, mo1499061165193
Location of the de novo IAACAL MCAL MCAL ICAL ACA
Size of previous IA, mm3.03.53.02.03.0
Time from first positive to last MRA, mo001982484
Size of the de novo IA, mm23223
GenotypePKD1TPKD1NTPKD1TPKD1NTPKD1T
Family history of IA/SAHYesYesYesYesYes
HypertensionYesYesYesYesYes
Treatment with ACEI or ARBYesYesYesYesYes
DyslipidemiaYesYesNoYesNo
StatinsYesYesNoYesNo
History of smokingNoNoNoYesNo
eGFR at first MRA, ml/min per 1.73 m21413494457
eGFR at last follow-up, ml/min per 1.73 m2TXTXTXTXTX
DeathNoNoNoNoNo
  • MRA, magnetic resonance angiography; W, women; M, men; IA, intracranial aneurysm; MCA, middle cerebral artery; R, right; ACA, anterior cerebral artery; SCA, superior cerebellar artery; BA, basilar artery; L, left; SAH, subarachnoid hemorrhage; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; TX, kidney transplant.