Table 4.

One-year all-cause mortality for participants diagnosed with active tuberculosis

Study groupsN of deaths/TBUnivariable AnalysisModel 1aModel 2b
HR (95% CI)P ValueAdjusted HR (95% CI)P ValueAdjusted HR (95% CI)P Value
Matched control87/1518ReferenceReferenceReference
Predialysis CKDc149/17041.54 (1.18 to 2.01)<0.0011.77 (1.36 to 2.31)<0.0011.68 (1.28 to 2.22)<0.001
 Stage 17/1170.99 (0.46 to 2.15)0.992.60 (1.17 to 5.81)0.022.16 (0.96 to 4.87)0.06
 Stage 26/1570.68 (0.30 to 1.55)0.361.20 (0.52 to 2.77)0.671.09 (0.47 to 2.53)0.84
 Stage 3121/13361.59 (1.21 to 2.10)<0.0011.67 (1.13 to 2.21)<0.0011.60 (1.20 to 2.13)0.001
 Stage 4/5 without dialysis15/943.00 (1.73 to 5.19)<0.0013.78 (2.19 to 6.55)<0.0013.49 (2.01 to 6.09)<0.001
  • TB, tuberculosis; HR, hazard ratio; 95% CI, 95% confidence interval.

  • a Model 1 was adjusted for age, sex, low-income states, and smoking histories.

  • b Model 2 was adjusted for age, sex, low-income status, smoking histories, places of residence (rural or urban), history of diabetes mellitus, hypertension, cancer, chronic obstructive pulmonary disease, immunosuppressants usage history, and baseline body mass index.

  • c Stages of CKD were determined as stage 1 (eGFR≥90 ml/min per 1.73 m2 with consecutive albuminuria), stage 2 (eGFR≥60 and <90 ml/min per 1.73 m2 with consecutive albuminuria), stage 3 (eGFR≥30 and <60 ml/min per 1.73 m2), and stage 4/5 without dialysis (eGFR<30 ml/min per 1.73 m2 but not on kidney replacement therapy).