Table 1.

Characteristics of older live kidney donors at donation in the United States, 1999–2016

CharacteristicsaHypertension, n=2265bNo Hypertension, n=22,268
Age, mean (SD), yr57 (6)56 (5)
Age category, %
 50–543748
 55–593131
 60–642115
 ≥65116
Women6065
Race/ethnicity, %
 White8482
 Black66
 Hispanic68
 Asian33
 Otherc11
Education level, %d
 ≤High school3029
 Attended college2425
 College graduate2929
 Post college1717
BMI, mean (SD)e28 (4)27 (4)
BMI category, %
 ≤242436
 25–294844
 ≥302820
Smokerf2529
BP, mm Hg, mean (SD)g
 Systolic BPh138 (15)123 (13)
 Diastolic BPh80 (10)74 (9)
Creatinine mg/dl, mean (SD)i0.88 (0.26)0.86 (0.31)
eGFR, ml/min per 1.73 m2, mean (SD)87 (14)89 (14)
Biologically related to the recipient, %5046
  • Body mass index (BMI) calculated as weight in kilograms divided by height in meters squared.

  • a Characteristics at the time of donation (1999–2016) are shown; age, sex, race/ethnicity, and biologic relationship to the recipient were available throughout the study period.

  • b Hypertension was defined as predonation documented use of antihypertensive therapy/history of hypertension for the period 2004–2016, regardless of systolic and diastolic BP; or predonation systolic BP ≥140 or diastolic BP ≥90 mm Hg when there was no available documentation of antihypertensive therapy for the period 1999–2003 (8% missing between 1999 and 2016).

  • c Race/ethnicity, the category of “Other” included American Indian or Alaskan Native, Native Hawaiian or other Pacific Islander, and multiracial.

  • d Education: 36% missing between 1999 and 2003; 23% missing between 2004 and 2009; 7% missing between 2010 and 2016.

  • e BMI: 8% missing between 1999 and 2003; 6% missing between 2004 and 2009; 0.8% missing between 2010 and 2016.

  • f Smoking status: 100% missing between 1999 and 2003; 17% missing between 2004 and 2009; 0% missing between 2010 and 2016.

  • g BP: 0.2% missing between 1999 and 2003; 8% missing between 2004 and 2009; 1% missing between 2010 and 2016.

  • h Mean (SD) systolic and diastolic BP were 132 (15) and 78 (9) mm Hg for donors with documented use of antihypertensive therapy versus 124 (14) and 74 (9) mm Hg for those not using antihypertensive therapy for the period 2004–2016.

  • i Creatinine/eGFR: 0.8% missing between 1999 and 2003; 2% missing between 2004–2009; 0.4% missing between 2010 and 2016.