Table 1.

Descriptive statistics for transplant recipients with tacrolimus or mycophenolic acid prescription drug events through Medicare Part D during 2008–2013, by organ type

VariableKidneyLiverHeart
Number of transplant recipients27,62515,8826851
Number of transplants27,73615,9586874
Yr of transplant
 1987–1990223 (1%)216 (1%)124 (2%)
 1991–19951007 (4%)1003 (6%)539 (8%)
 1996–20004146 (15%)2637 (17%)1341 (20%)
 2001–20058560 (31%)4643 (29%)1949 (28%)
 2006–201010,963 (40%)5753 (36%)2266 (33%)
 2011–20132726 (10%)1630 (10%)632 (9%)
Male15,787 (57%)9638 (61%)4980 (73%)
Racea
 White14,382 (52%)11,409 (72%)4954 (72%)
 Black6869 (25%)1345 (9%)1150 (17%)
 Hispanic/Latino4417 (16%)2308 (15%)551 (8%)
 Asian/Other1956 (7%)815 (5%)196 (3%)
Age at transplant, yr
 Median (IQR)52 (39–61)54 (48–60)54 (45–60)
 <181023 (4%)145 (1%)107 (2%)
 18–343979 (14%)824 (5%)712 (10%)
 35–497002 (25%)3861 (24%)1577 (23%)
 50–6411,762 (43%)9779 (62%)3919 (57%)
 65+3859 (14%)1273 (8%)536 (8%)
Age at first Medicare Part D claim during 2008–2013, yr
 Median (IQR)58 (45–66)60 (53–65)62 (50–66)
 <18557 (2%)3 (0.0%)5 (0.1%)
 18–342891 (11%)647 (4%)597 (9%)
 35–495620 (20%)1894 (12%)989 (14%)
 50–649618 (35%)7992 (50%)2630 (38%)
 65+8939 (32%)5346 (34%)2630 (38%)
BMIa
 <18.51071 (4%)372 (3%)263 (4%)
 18.5–24.98519 (35%)4375 (30%)2429 (37%)
 25.0–29.97773 (32%)5182 (35%)2400 (37%)
 ≥306870 (28%)4810 (33%)1404 (22%)
Donor typea
 Donation after circulatory death1410 (5%)474 (3%)
 Donation after brain death15,446 (57%)14,186 (93%)
 Living related donation6933 (26%)382 (3%)
 Living unrelated donation3319 (12%)140 (1%)
Previous transplant of the same organ type3010 (11%)884 (6%)145 (2%)
Number of human leukocyte antigen mismatches: 1–6 versus 0a23,865 (88%)
Recipient diagnosis (kidney)a
 Diabetes6168 (23%)
 Hypertension6140 (22%)
 GN6943 (25%)
 Cystic kidney disease2410 (9%)
 Other5728 (21%)
Recipient diagnosis (liver)b
 Acute hepatic necrosis933 (6%)
 Cholestatic liver disease/cirrhosis2011 (13%)
 Noncholestatic cirrhosis7933 (50%)
 Hepatitis C6408 (40%)
 Malignant neoplasm2812 (18%)
 Metabolic disease584 (4%)
 Other liver disease2307 (15%)
Recipient diagnosis (heart)a
 Coronary artery disease2925 (43%)
 Cardiomyopathy3416 (50%)
 Congenital/valvular/other501 (7%)
Ventricular assist device (heart)a1746 (38%)
  • Data displayed as n (%) unless otherwise noted. IQR, interquartile range; BMI, body mass index.

  • a Missing for at most 5% of patients, except BMI missing for 7% and 12% of Medicare Part D liver and kidney patients, respectively, and ventricular assist device missing for 33% of Medicare Part D heart patients.

  • b Diagnoses for liver transplant recipients are on the basis of primary and secondary diagnoses and are not mutually exclusive. Each liver recipient can have one or two diagnoses; therefore, percentages will not sum to 100%.