Table 1.

Baseline characteristics of control patients and patients continuing loop diuretics

CharacteristicsControl Patients, n=6078Patients Continuing Loop Diuretics,an=5219Standardized Difference, %
Age, yr−14.1
 Mean±SD70±1268±12
 Median [p25, p75]72 [65, 79]70 [61, 77]
Sex, n (%)−1.9
 Men2860 (47)2505 (48)
 Women3218 (53)2714 (52)
Race, n (%)4.4
 White3359 (55)2832 (54)
 Black1573 (26)1360 (26)
 Hispanic726 (12)663 (13)
 Asian190 (3)189 (4)
 Other/unknown230 (4)175 (3)
Vascular access, n (%)22.9
 Arteriovenous fistula984 (16)1259 (24)
 Arteriovenous graft354 (6)413 (8)
 Central venous catheter4712 (77)3518 (67)
 Missing/unknown28 (1)29 (1)
Etiology of ESKD, n (%)3.8
 Diabetes3285 (54)2899 (56)
 Hypertension1723 (28)1469 (28)
 Other1070 (18)851 (16)
Charlson comorbidity index score−8.2
 Mean±SD6.3±1.66.2±1.6
 Median [p25, p75]6.0 [5.0, 7.0]6.0 [5.0, 7.0]
24-h urine ≥200 ml, n (%)1853 (31)2086 (40)19.6
Vintage, d−4.6
 Mean±SD23±2022±18
 Median [p25, p75]18 [9, 27]18 [9, 27]
Prior transplant, n (%)13 (0.2)13 (0.3)0.7
Nephrology care before dialysis initiation, n (%)13.7
 Yes3923 (65)3687 (71)
 No1356 (22)911 (17)
 Did not report798 (13)621 (12)
Diabetes, n (%)4557 (75)4023 (77)4.9
Heart failure, n (%)790 (13)667 (13)−0.7
Cerebrovascular disease, n (%)69 (1)58 (1)−0.2
Coronary artery disease677 (11)566 (11)−0.9
Predialysis systolic BP, mm Hg
 Mean±SD144±21145±20
 Median [p25, p75]144 [130, 159]145 [132, 158]5.7
Postdialysis systolic BP, mm Hg
 Mean±SD143±20144±19
 Median [p25, p75]142 [129, 156]143 [130, 157]6.5
Ultrafiltration volume, L
 Mean±SD2.1±1.32.0±1.3−6.5
 Median [p25, p75]2.0 [1.4, 2.7]1.9 [1.3, 2.6]
Ultrafiltration rate, ml/kg per hour
 Mean±SD8.3±8.17.9±8.7−4.4
 Median [p25, p75]7.3 [5.1, 10.0]6.9 [4.7, 9.5]
Prescribed treatment time, min
 Mean±SD213±48213±56
 Median [p25, p75]210 [195, 240]210 [184, 240]−1.5
Delivered treatment time, min
 Mean±SD212±25210±26−5.3
 Median [p25, p75]212 [191, 232]211 [188, 229]
Target weight, kg
 Mean±SD81.6±22.583.1±23.76.6
 Median [p25, p75]78.0 [65.8, 94.2]79.7 [66.0, 95.8]
Postdialysis weight, kg
 Mean±SD81.1±22.382.6±23.6
 Median [p25, p75]77.5 [65.4, 93.6]78.9 [65.6, 95.4]6.5
Interdialytic weight gain, kg
 Mean±SD2.0±1.52.0±1.4−4.3
 Median [p25, p75]1.9 [1.3, 2.6]1.8 [1.2, 2.5]
Albumin, g/dl
 Mean±SD3.5±0.53.6±0.521.7
 Median [p25, p75]3.5 [3.2, 3.8]3.6 [3.3, 3.9]
Potassium, mEq/L
 Mean±SD4.3±0.64.3±0.6−0.9
 Median [p25, p75]4.3 [3.9, 4.7]4.3 [3.9, 4.7]
  • p25, 25th percentile; p75, 75th percentile.

  • a Patients continuing loop diuretics refilled a prescription for a loop diuretic immediately after dialysis initiation, whereas control patients did not.