Table 1.

Baseline sleep duration and clinical characteristics of 1601 patients

CharacteristicSleep Duration (h)
≤5.05.1–6.06.1–7.07.1–8.0>8.0
Number152300541420188
Sleep duration, h4.7±0.75.9±0.26.9±0.27.8±0.29.2±0.7
Age, yr60 (52–66)57 (47–66)60 (51–68)63 (57–70)68 (61–72)
Men, N (%)96 (63)179 (60)341 (63)291 (69)124 (66)
Smoking status, N (%)
 Nonsmokers79 (52)174 (58)301 (56)197 (47)102 (54)
 Past smokers39 (26)72 (24)158 (29)158 (38)54 (29)
 Current smokers34 (22)54 (18)82 (15)65 (15)32 (17)
Diabetes, N (%)55 (36)114 (38)164 (30)150 (36)75 (40)
Cardiovascular disease, N (%)27 (18)55 (18)100 (18)99 (24)49 (26)
Body mass index, kg/m224.4±4.223.5±4.223.4±3.723.5±3.423.0±3.7
Systolic BP, mm Hg131±20131±18132±19131±17132±17
Diastolic BP, mm Hg77±1277±1178±1277±1175±11
Serum creatinine, mg/dl1.7 (1.3–2.4)1.7 (1.3–2.4)1.8 (1.4–2.5)1.9 (1.5–2.6)2.0 (1.5–2.7)
eGFR, ml/min per 1.73 m233 (21–40)32 (21–40)29 (20–37)28 (19–37)25 (17–34)
 45–59, N (%)18 (12)40 (13)56 (10)28 (7)12 (6)
 30–44, N (%)64 (42)127 (42)206 (38)168 (40)55 (29)
 15–29, N (%)49 (32)107 (36)224 (41)166 (40)89 (47)
 10–14, N (%)21 (14)26 (9)55 (10)58 (14)32 (17)
Urinary albumin excretion, g/gCr0.46 (0.12–1.10)0.44 (0.11–1.33)0.54 (0.15–1.24)0.47 (0.13–1.29)0.39 (0.08–1.18)
C-reactive protein, mg/dla0.10 (0.04–0.21)0.06 (0.04–0.19)0.07 (0.04–0.20)0.08 (0.04–0.18)0.10 (0.04–0.21)
Medications, N (%)
 RAS blockade128 (84)243 (81)449 (83)351 (84)153 (81)
 Hypnotics
  None116 (76)251 (84)480 (89)357 (85)158 (84)
  ≤2 times/wk13 (9)18 (6)23 (4)15 (4)6 (3)
  ≥3 times/wk23 (15)31 (10)38 (7)48 (11)24 (13)
Beck depression inventory score11 (6–18)8 (5–13)6 (3–11)6 (3–11)7 (4–12)
 ≥11, N (%)82 (54)112 (37)155 (29)114 (27)61 (32)
PSQI global score10 (8–13)6 (5–9)4 (3–6)3 (2–5)3 (2–4)
 ≥6, N (%)140 (92)185 (62)164 (30)70 (17)29 (15)
Sleep duration
 At 2 yrb, h5.4±1.36.3±0.86.8±0.97.6±1.08.4±1.3
 At 3.5 yrc5.4±1.26.2±0.96.9±0.97.6±1.38.4±1.3
  • Data presented as mean±SD or median (interquartile range), unless otherwise specified. Cr, creatinine; RAS, renin angiotensin system; PSQI, Pittsburgh Sleep Quality Index.

  • a n=113, 232, 415, 314, and 149 for patients with ≤5.0, 5.1–6.0, 6.1–7.0, 7.1–8.0, and >8.0 h baseline sleep duration, respectively.

  • b n=101, 201, 387, 307, and 126 for patients with ≤5.0, 5.1–6.0, 6.1–7.0, 7.1–8.0, and >8.0 h baseline sleep duration, respectively.

  • c n=64, 153, 275, 188, and 82 for patients with ≤5.0, 5.1–6.0, 6.1–7.0, 7.1–8.0, and >8.0 h baseline sleep duration, respectively.