Table 4.

PSQI global score and incidence of ESKD in 1601 patients with CKD

PSQI Global ScoreNRI (95% CI) of
PSQI (≤5 versus ≥6)
≤5≥6
Number1013588
Incidence of ESKD, N (%)172 (17)110 (19)
Incidence rate (per person-year)0.0490.055
Adjusted hazard ratio (95% CI)
 Model 11.00 (reference)1.19 (0.93 to 1.51)0.02 (−0.04 to 0.09)
 Model 21.00 (reference)1.39 (1.09 to 1.77)a0.02 (−0.34 to 0.09)
 Model 31.00 (reference)1.40 (1.09 to 1.79)a0.03 (−0.12 to 0.11)
 Model 4b1.00 (reference)1.33 (1.03 to 1.71)a0.03 (−0.21 to 0.10)
  • Model 1 adjusted for age (yr) and sex. Model 2 adjusted for the covariates in model 1, eGFR (ml/min per 1.73 m2), and urinary albumin excretion (log g/gCr). Model 3 adjusted for the covariates in model 2, smoking status (non-, past, or current smoker), body mass index (kg/m2), history of diabetes mellitus and cardiovascular disease, systolic BP (mm Hg), and blockade of renin angiotensin system. Model 4 adjusted for the covariates in model 3 and Beck depression inventory (≤10 versus >10). PSQI, Pittsburgh Sleep Quality Index; NRI, net reclassification index; 95% CI, 95% confidence interval; Cr, creatinine.

  • a P<0.05.

  • b P for interaction of PSQI global score with age, sex, history of diabetes, and cardiovascular disease=0.20, 0.14, 0.71, and 0.52, respectively.