Table 5.

Association between biopsy histologic classification and post-transplant outcomes

ParameterDeath-Censored Graft Failure, n=87Death, n=98
N (%)HR (95% CI)N (%)HR (95% CI)
UnadjustedAdjustedaUnadjustedAdjusteda
Procurement biopsies
 Optimal histology48 (28)ReferenceReference61 (35)
 Suboptimal histology39 (40)1.51 (0.98 to 2.30)1.30 (0.84 to 2.02)37 (38)1.00 (0.66 to 1.52)0.92 (0.60 to 1.41)
Reperfusion biopsies
 Optimal histology32 (22)ReferenceReference46 (31)
 Suboptimal histology55 (45)2.25 (1.45 to 3.48)1.93 (1.20 to 3.12)52 (43)1.21 (0.81 to 1.80)0.87 (0.56 to 1.35)
Combination
 Optimal histology on both biopsies22 (20)ReferenceReference32 (29)
 Suboptimal procurement biopsy histology only10 (27)1.48 (0.70 to 3.14)1.30 (0.61 to 2.76)14 (38)1.41 (0.75 to 2.64)1.46 (0.77 to 2.76)
 Suboptimal reperfusion biopsy histology only26 (43)2.39 (1.35 to 4.25)2.02 (1.09 to 3.74)29 (48)1.55 (0.93 to 2.56)1.14 (0.67 to 1.94)
 Suboptimal histology on both biopsies29 (48)2.61 (1.50 to 4.54)2.17 (1.19 to 3.94)23 (38)1.11 (0.64 to 1.91)0.80 (0.45 to 1.43)
  • HR, hazard ratio, 95% CI, 95% confidence interval.

  • a Models are adjusted for kidney donor risk index, recipient age, and dialysis vintage.