Table 2.

Demographics and clinical characteristics by cohort for the International Database of Ambulatory BP in Renal Patients

CovariateOverall (n=7518)AASK (n=587)CRIC (n=1283)Italian Cohort (n=428)CKD-JAC (n=1067)Spanish Cohort (n=4153)
Age, yr65 (12)61 (10)64 (10)66 (14)61 (11)68 (13)
Men, N (%)4080 (54)370 (63)732 (57)252 (59)675 (63)2051 (49)
Race, N (%)
 Black1092 (14)587 (100)505 (39)0 (0)0 (0)0 (0)
 Other1229 (16)0 (0)162 (13)0 (0)1067 (100)0 (0)
 White5197 (69)0 (0)616 (48)428 (100)0 (0)4153 (100)
Body mass index, kg/m229 (6)31 (7)32 (7)29 (5)23 (4)29 (5)
Current smoker, N (%)941 (12)104 (18)113 (9)98 (23)138 (13)488 (12)
Prior smoker, N (%)1465 (20)345 (59)684 (53)N/A436 (41)N/A
Medications, N (%)
β blockers2280 (30)246 (42)692 (54)154 (36)184 (17)1004 (24)
 Diuretics3531 (47)498 (85)717 (56)119 (28)306 (29)1891 (46)
 ACEI/ARBs4582 (61)491 (84)870 (68)363 (85)858 (80)2000 (48)
 Calcium channel blockers2949 (39)168 (29)583 (45)207 (48)587 (55)1404 (34)
 Vasodilators438 (6)171 (29)187 (15)80 (19)0 (0)N/A
No. Htn meds2.44 (1.48)3.63 (1.35)2.69 (1.43)2.75 (1.41)2.25 (1.46)2.22 (1.43)
Diabetes, N (%)2620 (35)56 (9.5)583 (45)161 (38)378 (35)1442 (35)
Stroke/TIA, N (%)757 (10)106 (18)160 (12)33 (8)125 (12)333 (8)
Peripheral vascular disease, N (%)233 (3)35 (6)96 (7.5)31 (7)71 (7)N/A
Coronary artery disease, N (%)1119 (15)81 (14)375 (29)82 (19)138 (13)443 (11)
Heart failure, N (%)454 (6)58 (10)134 (10)22 (5)42 (4)198 (5)
Cardiovascular disease (w/o PVD), N (%)1928 (26)203 (35)508 (40)119 (28)248 (23)850 (20)
Serum creatinine, mg/dl1.7 (1.1)2.4 (1.4)2.1 (1.2)2.0 (1.1)2.2 (1.2)1.3 (0.7)
eGFR, ml/min per 1.73 m248 (23)37 (14)38 (15)40 (19)28 (12)58 (23)
eGFR groups, N (%)
 <15418 (6)41 (7)74 (6)37 (9)178 (17)88 (2)
 15–301253 (17)150 (26)330 (26)107 (25)436 (41)230 (6)
 30–451908 (25)221 (38)461 (36)121 (28)348 (33)757 (18)
 45–602621 (35)165 (28)363 (28)116 (27)100 (9)1877 (45)
 60+1318 (18)10 (2)55 (4)47 (11)5 (0.5)1201 (29)
Proteinuria, N (%)
 Normal/mild1792 (24)338 (58)464 (36)111 (26)117 (11)762 (18)
 Moderate2199 (29)106 (18)288 (22)133 (31)298 (28)1374 (33)
 Severe1547 (21)139 (24)360 (28)184 (43)637 (60)227 (6)
 Missing1980 (26)4 (0.7)171 (13)0 (0)15 (1)1790 (43)
  • Values presented are N (%) or mean (SD) where indicated. Proteinuria was categorized as mild (urine albumin-to-creatinine ratio <30 mg/g [Spanish cohort], 24-h urine protein <150 mg [AASK, Italian cohort, and CKD-JAC], and urine protein-to-creatinine ratio <150 mg/g [CRIC]), moderate, or severe (urine albumin-to-creatinine ratio >300 mg/g, 24-h urine protein >500 mg, and urine protein-to-creatinine ratio >500 mg/g). AASK, African American Study of Kidney Disease and Hypertension Cohort Study; CRIC, Chronic Renal Insufficiency Cohort; CKD-JAC, Chronic Kidney Disease Japan Cohort; N/A, not available; ACEI/ARBs, angiotensin converting enzyme inhibitors/angiotensin receptor blockers; Htn, hypertension; TIA, transient ischemic attack; w/o, without; PVD, peripheral vascular disease.