Table 2.

Most common glomerular disease diagnoses among 7962 children who underwent kidney biopsy in China from 2004 to 2014 by clinical presentation, sex, and age

Clinical SyndromeSexAge Group, yr
BoysGirls0–1213–18
Nephrotic syndrome (%)
 Top 1MCD (62)MCD (28)MCD (47)MCD (54)
 Top 2IgAN (10)LN (20)IgAN (13)MN (12)
 Top 3FSGS (8)MN (18)FSGS (10)IgAN (10)
Proteinuria and hematuria (%)
 Top 1IgAN (35)HSPN (27)HSPN (39)IgAN (37)
 Top 2HSPN (32)IgAN (26)IgAN (22)HSPN (23)
 Top 3MsPGN (11)LN (20)MsPGN (14)LN (13)
Proteinuria (%)
 Top 1MsPGN (29)LN (28)HSPN (50)MsPGN (26)
 Top 2HSPN (27)HSPN (23)MsPGN (26)LN (19)
 Top 3IgAN (14)MsPGN (18)LN (11)IgAN (16)
Hematuria (%)
 Top 1MsPGN (31)TBMN (32)MsPGN (36)IgAN (33)
 Top 2IgAN (28)MsPGN (32)TBMN (26)TBMN (21)
 Top 3TBMN (19)IgAN (12)IgAN (16)MsPGN (20)
AKI (%)
 Top 1MCD (40)LN (42)EPGN (27)MCD (30)
 Top 2LN (12)EPGN (13)MCD (19)LN (25)
 Top 3FSGS (12)CrGN (11)LN (17)IgAN (8)
Progressive CKD (%)
 Top 1IgAN (39)PSGN (21)IgAN (24)IgAN (32)
 Top 2FSGS (12)IgAN (15)HSPN (16)PSGN (19)
 Top 3HSPN (11)LN (15)FSGS (13)FSGS (11)
  • MCD, minimal change disease; IgAN, IgA nephropathy; LN, lupus nephritis; MN, membranous nephropathy; HSPN, Henoch–Schonlein purpura nephritis; MsPGN, mesangial proliferative GN; TBMN, thin basement membrane nephropathy; EPGN, endocapillary proliferative GN; CrGN, crescent GN; PSGN, proliferative sclerosing GN.