Table 1.

Comparison of patient characteristics by AKI (yes/no)

VariablesSerum Creatinine OnlySerum Creatinine and Urine Output
No AKI (n=1276)AKI (n=299)No AKI (n=1267)AKI (n=355)
Baseline characteristics
 Age, yr5 (11)5 (10)5 (11)6 (11)
 Female sex583 (46%)143 (48%)574 (45%)168 (47%)
 Sainte-Justine Hospital822 (64%)212 (71%)803 (63%)255 (72%)
 Admission diagnosis
  Cardiac (nonsurgical)69 (5%)26 (9%)71 (6%)28 (8%)
  Trauma158 (12%)26 (9%)151 (12%)37 (10%)
  Kidney4 (0.3%)15 (5%)4 (0.3%)15 (4%)
  Infection (excluding bronchiolitis)253 (20%)67 (22%)244 (19%)86 (24%)
  Neurologic/neurosurgical217 (17%)32 (11%)216 (17%)41 (12%)
  Gastrointestinala44 (4%)26 (9%)45 (4%)27 (8%)
  Oncologic43 (3%)12 (4%)43 (3%)12 (3%)
  Respiratory121 (10%)31 (10%)125 (10%)34 (10%)
  Diabetes14 (1%)18 (6%)17 (1%)18 (5%)
  Otherb353 (28%)46 (15%)351 (28%)57 (16%)
 Baseline kidney abnormality22 (2%)26 (9%)22 (2%)27 (8%)
 Postoperative (noncardiac)485 (38%)87 (29%)481 (38%)101 (29%)
 PRISM score6 (6)9 (10)6 (6)9 (9)
 PRISM death rate (%)1.9 (3.3)3.2 (9.2)1.9 (3.4)2.8 (7.3)
Treatment characteristics
 Nephrotoxic antibiotics289 (23%)111 (37%)278 (22%)126 (36%)
 Vasopressors87 (7%)72 (24%)77 (6%)82 (23%)
 Steroids339 (27%)116 (39%)336 (27%)130 (37%)
 Mechanically ventilated (yes/no)526 (41%)146 (49%)510 (40%)185 (52%)
 Length of mechanical ventilation, d0 (2)0 (4)0 (2)1 (4)
Kidney related
 Nephrology consultation during admission49 (4%)76 (25%)47 (4%)80 (23%)
 Kidney Replacement Therapy012 (4%)012 (3%)
Outcomes
 Intensive care length of stay, d1.4 (2.3)2.5 (5.8)1.3 (2.1)2.7 (6.0)
 Hospital length of stay, d9 (12)13 (19)9 (11)13 (19)
  • Continuous variables presented as median (interquartile range) and categoric variables presented as number (percentage). PRISM, Pediatric Risk of Mortality.

  • a Gastrointestinal includes liver, stomach, pancreas, and intestine.

  • b Includes hematologic (nononcologic), inborn error of metabolism and metabolic (noninborn error of metabolism), immunologic, intoxication, burn, orthopedic, otolaryngologic, endocrinologic (nondiabetes), and bronchiolitis.