Table 2.

Baseline characteristics of 481 participants in the NEFRONA cohort study according to atherosclerosis progression over the subsequent 2 years

CharacteristicNo (n=192)Yes (n=289)P (No versus Yes)
Age, yr56 (42–65)63 (56–69)<0.001
Men, N (%)109 (57)186 (64)0.10
Ever smoker, N (%)100 (52)183 (63)0.01
Dyslipidemia, N (%)126 (66)210 (73)0.11
Diabetes mellitus, N (%)40 (21)97 (34)0.002
Hypertension, N (%)171 (89)271 (94)0.04
Systolic BP, mm Hg137 (18)145 (21)<0.001
Diastolic BP, mm Hg80 (10)81 (11)0.29
Total cholesterol, mg/dl179 (156–202)183 (157–213)0.31
LDL cholesterol, mg/dl102 (85–123)105 (86–129)0.39
HDL cholesterol, mg/dl48 (40–61)47 (37–58)0.15
Triglycerides, mg/dl109 (82–163)137 (103–176)0.001
Glucose, mg/dl95 (86–105)102 (91–123)<0.001
25-hydroxyvitamin D, ng/ml17.2 (11.8–22.3)16.2 (11.9–20.7)0.54
IMT, mm0.72 (0.59–1.01)0.92 (0.75–1.14)<0.001
HsCRP, mg/L1.87 (1.02–3.77)2.49 (1.23–5.17)0.01
CKD stage, N (%)0.36
 3104 (54)139 (48)
 4–572 (38)127(44)
 Dialysis16 (8)23 (8)
Plaque presence at baseline, N (%)109 (57)226 (78)<0.001
  • Dyslipidemia: diagnosis of dyslipidemia in the clinical history. Data are median (25th to 75th percentile) for quantitative variables non-normally distributed, mean (SD) for normal variables, and number (percentage) for categorical variables. IMT, average intima-media thickness; HsCRP, high-sensitivity C-reactive protein.