Table 2.

Risk of left ventricular hypertrophy and model discrimination by different systolic BP index parameters in unadjusted and adjusted analyses

Metric, n=513aUnadjusted ORb (95% CI)Unadjusted c Statistic (95% CI)Adjusted ORb,c (95% CI)Adjusted c Statistic (95% CI)
Clinic systolic BP index measurements at a single visit1.8 (1.4 to 2.4)0.65 (0.56 to 0.73)1.6 (1.2 to 2.3)0.79 (0.73 to 0.85)
Mean of all clinic systolic BP indices at up to two visits2.0 (1.5 to 2.8)0.65 (0.58 to 0.73),Reference1.8 (1.3 to 2.6)0.80 (0.74 to 0.85),Reference
Mean ABP wake systolic BP index1.8 (1.3 to 2.4)0.64 (0.57 to 0.71)1.8 (1.2 to 2.6)0.80 (0.70 to 0.86)
Mean ABP sleep systolic BP index1.5 (1.2 to 2.0)0.63 (0.56 to 0.71)1.5 (1.10 to 2.1)0.80 (0.74 to 0.85)
Mean of all clinic systolic BP indices at up to two visits + mean ABP wake systolic BP indexClinic:1.8 (1.2 to 2.6); ABP:1.3 (0.9 to 1.9)0.67 (0.60 to 0.75)Clinic:1.5 (1.0 to 2.4); ABP:1.4 (0.9 to 2.2)0.80 (0.75 to 0.86)
  • OR, odds ratio; 95% CI, 95% confidence interval; ABP, ambulatory BP.

  • a No differences were noted in the c statistics of any metric compared with that for the reference group, which includes clinic systolic BPs at up to two sequential clinic visits.

  • b OR for every 0.1 increase in systolic BP index.

  • c Adjusted for age, sex, race, cause of CKD, body mass index z score, duration of CKD, urine protein-to-creatinine ratio, serum albumin, hemoglobin, antihypertensive use, and baseline eGFR (by bedside Schwartz); n=496 included because of missing covariates.