Variables | All, n=190 | C4d+, n=38 | C4d−, n=152 |
---|---|---|---|

Age, yr, mean±SD | 29±14 | 28±16 | 29±19 |

Men (%) | 123 (65) | 24 (63) | 99 (65) |

Body mass index, kg/m^{2}, median [IQR] | 21.8 [19.6–22.9] | 21.9 [19.8–23.7] | 21.7 [19–23.1] |

Smoker, n (%) | 38 (20) | 8 (21) | 30 (20) |

Macroscopic hematuria, n (%) | 81 (43) | 16 (42) | 65 (43) |

Systolic BP, mm Hg, mean±SD | 121±13 | 120±13 | 119±16 |

Diastolic BP, mm Hg, mean±SD | 68±10 | 71±10 | 76±10 |

Hypertension, n (%) | 24 (13) | 6 (16) | 18 (12) |

Serum creatinine, mg/dl, median [IQR] | 1.0 [0.8–1.0] | 1.0 [0.8–1.1] | 1.0 [0.9–1.1] |

eGFR, ml/min per 1.73 m^{2}, median [IQR] | 100 [86–112] | 98 [88–110] | 99 [89–115] |

eGFR categories, n (%) | |||

81–90 | 43 (23) | 9 (24) | 34 (22) |

91–100 | 95 (50) | 18 (47) | 77 (51) |

>100 | 52 (27) | 11 (29) | 41 (27) |

Protein-to-creatinine ratio, g/g, median [IQR]^{a} | 18 [0.8–3.9] | 1.9 [0.9–3.1] | 1.5 [0.9–2.2] |

Histopathologic Oxford classification, n (%) | |||

M1 | 57 (30) | 15 (39) | 42 (28) |

S1 | 22 (12) | 6 (16) | 16 (11) |

E1 | 19 (10) | 5 (13) | 14 (9) |

Interstitial fibrosis | |||

T0: <25% | 133 (70) | 23 (61) | 110 (72) |

T1: 25%–50% | 40 (21) | 12 (32) | 28 (18) |

T2: >50% | 17 (9) | 3 (8) | 14 (9) |

Glomeruli with crescents median [IQR] | 1.1 [0–2] | 1.5 [0–4] | 1.3 [0–2] |

IQR, interquartile range; M, mesangial cellularity; S, segmental sclerosis; E, endocapillary hypercellularity; T, interstitial fibrosis and tubular atrophy.

↵a For protein-to-creatinine ratio (grams per gram) median [IQR], the

*P*value among all variables was statistically significant at*P*=0.04.