Table 4.

Characteristics stratified by histopathologic class: Biopsy specimen characteristics

CharacteristicFocal (n=15)Crescentic (n=68)Mixed (n=25)Sclerotic (n=10)P Value
Total number of glomeruli22±1217±919±919±90.35
Normal glomeruli, percentage71 (62–90)0 (0–8)9 (0–31)0 (0–0)<0.001
Cellular crescents, percentage12±1081±1632±1519±16<0.001
Sclerotic glomeruli, percentage0 (0–5)0 (0–14)17 (8–30)63 (58–70)<0.001
Interstitial fibrosis  and tubular atrophy<0.001
 08 (53)16 (24)1 (4)0 (0)
 17 (47)30 (44)11 (44)1 (10)
 20 (0)19 (28)10 (40)3 (30)
 30 (0)3 (4)3 (12)6 (60)
Interstitial infiltrate0.16
 05 (33)5 (8)1 (4)1 (10)
 19 (60)17 (25)12 (48)2 (20)
 21 (7)22 (32)6 (24)7 (70)
 30 (0)24 (35)6 (24)0 (0)
Tubulitis0.02
 012 (80)27 (40)15 (60)6 (60)
 13 (20)41 (60)10 (40)4 (40)
  • Data are number (%), mean±SD, or median (interquartile range). Excluding five patients without kidney biopsy samples available for re-evaluation. Total, n=118 patients.