Table 1.

Pre- and postprobabilities of CKD on the basis of genetic test

Age Group, yrPrevalence of CKD,a,b %Probability of CKD if Test Is Positive (Positive Predictive Value),c %Probability of Disease if Test Is Negative (1− Negative Predictive Value),c %
40–5944.23.9
60–691313.512.6
≥703637.035.3
  • a CKD is defined as an eGFR<60 ml/min per 1.73 m2.

  • b Prevalence is estimated from the work by Coresh et al. (5) on the basis of the National Health and Nutrition Examination 1999–2004 data.

  • c Calculations are on the basis of a reported odds ratio of 1.08 and a minor allele frequency of 43% shroom family member 3.