Table 2.

Comparison of baseline characteristics of 402 patients with kidney biopsies by development of ESRD during follow-up

VariablesNon-ESRD, n=334ESRD, n=68P Value
Age, yr41 (31–50)43(31–51)0.51
Women, %44340.13
Follow-up, mo35.8 (24.5–83.1)42.8 (27.1–63.8)0.94
eGFR ml/min per 1.73 m291 (61–113)57 (34–83)<0.001
Systolic BP, mmHg129 (120–140)140 (125–150)0.11
Urine protein, g/24 h1.9 (1.0–4.4)3.7 (2.4–5.6)<0.001
Serum albumin, g/dl3.5 (2.6–4.1)3.6 (2.7–3.9)0.91
Urinary fibrinogen to Cr, ng/mg521.1 (177.5–1451.3)1599.9 (654.9–4148.6)<0.001
Global sclerosis, %8 (0–27)17 (33–58)<0.001
Segmental sclerosis, %0 (0–7)3 (0–14)0.01
IFTA1 (1–2)2 (1–2)<0.001
Disease type, n (%)<0.001
 IgAN130 (39)22 (32)
 IMN89 (27)5 (7)
 DN64 (19)37 (54)
 Focal segmental GN51 (15)4 (6)
  • Cr, creatinine; IFTA, interstitial fibrosis and tubular atrophy; IgAN, IgA nephropathy; IMN, idiopathic membranous nephropathy; DN, diabetic nephropathy.