Table 2.

Sustained virologic response rate by genotype and regimen used

GenotypeTotal Treated, NTotal with Sustained Virologic Response, NSustained Virologic Response Rate, %Early Discontinuation, N (%)
Genotype 1Aa overall5445833 (6)
 Sofosbuvir/ribavirin ×24 wk22100
 Sofosbuvir/simeprevir ×12 wk322578
 Sofosbuvir/simeprevir ×24 wk11100
 Sofosbuvir/ledipasvir ×12 wk11982
 Sofosbuvir/ledipasvir ×24 wk44100
 Sofosbuvir/ledipasvir/ribavirin ×12 wk22100
 Sofosbuvir/simeprevir/ribavirin ×12 wk22100
Genotype 1B overall1816892 (11)
 Sofosbuvir/ribavirin ×12 wk11100
 Sofosbuvir/ribavirin ×24 wk2150
 Sofosbuvir/simeprevir ×12 wk9889
 Sofosbuvir/ledipasvir ×12 wk55100
 Sofosbuvir/simeprevir/ribavirin ×12 wk11100
Genotype 21412861 (7)
 Sofosbuvir/ribavirin ×12 wk141286
Genotype 373432 (28)
 Sofosbuvir/ribavirin ×12 wk100
 Sofosbuvir/ribavirin ×24 wk6350
Genotype 453600 (0%)
 Sofosbuvir/ribavirin ×24 wk2150
 Sofosbuvir/ledipasvir ×12 wk3267
Total9879818 (8)
  • a Includes both genotype 1A and genotype 1 nonsubtypable.