Table 3.

Discriminating test characteristics of all frailty measurements used in the Geriatric Assessment in Older Patients Starting Dialysis Study and the prevalence of frailty according the tests

Screening ModalityCutoff ValuePrevalence of Frailty, %Sensitivity, %Specificity, %PPV, %NPV, %
Fried Frailty Index≥34859 (48–70)85 (66–96)92 (83–97)41 (34–49)
Groningen Frailty Indicator≥46774 (64–83)52 (33–70)82 (76–87)40 (29–52)
G8≤148892 (85–97)26 (12–45)79 (75–82)53 (31–74)
ISAR-HP≥26072 (61–81)79 (59–92)91 (83–96)48 (38–58)
VMS vulnerable elderly≥28290 (79–96)38 (19–59)78 (72–83)60 (37–79)
Frailty question≥56372 (61–82)67 (45–84)88 (80–93)42 (32–53)
  • PPV, positive predictive value; NPV, negative predictive value; G8, Geriatric8; ISAR-HP, Identification of Seniors at Risk-Hospitalized Patients; VMS, Veiligheidsmanagementsysteem (Hospital Safety Program criteria); frailty question, clinical judgment of the nephrologist.