Table 2.

Associations of era of home hemodialysis initiation with all-cause mortality, technique failure, and the composite of death and technique failure

DeathTechnique FailureDeath and Technique Failure
Incident Cohort PeriodEventsEvent Rates/100 Patient-YrEventsEvent Rates/100 Patient-YrEventsEvent Rates/100 Patient-Yr
1996–2002517.37412.012519.3
2003–2007 (ref)1277.91589.528517.4
2008–2012915.527116.836222.3
Unadjusted Hazard Ratio (95% CI)
Overall
 1996–20020.94 (0.68 to 1.31)1.10 (0.93 to 1.45)1.03 (0.83 to 1.27)
 2003–2007 (ref)111
 2008–20120.75 (0.56 to 0.99)1.51 (1.23 to 1.86)1.19 (1.01 to 1.40)
Adjusted Hazard Ratio (95% CI)
Overalla
 1996–20020.67 (0.38 to 1.21)1.39 (0.78 to 2.46)1.11 (0.71 to 1.74)
 2003–2007 (ref)111
 2008–20120.83 (0.58 to 1.19)1.51 (1.06 to 2.15)1.25 (0.98 to 1.61)
Yr 1a
 1996–20020.67 (0.31 to 1.49)1.49 (0.69 to 3.21)1.19 (0.62 to 2.26)
 2003–2007 (ref)111
 2008–20120.71 (0.43 to 1.20)2.45 (1.78 to 3.39)1.84 (1.41 to 2.38)
  • ref, referent group; 95% CI, 95% confidence interval.

  • a Adjusted for age, sex, race, body mass, vascular access type, dialysis vintage, home hemodialysis modality, region, facility size, distance, income quintile, primary diagnosis, diabetes, coronary artery disease, stroke, peripheral vascular disease, and smoking status.