Table 4.

Multivariate relationship between waitlisted patient and donor characteristics and outcomes of kidney offers

CharacteristicsTransplantReason for Offer Refusal
Donor-RelatedBypassRecipient-RelatedHistocompatibilityProgramOther
Waitlisted patient characteristics
Age, yr
  ≤251.001.001.001.001.001.001.00
  26–451.05 (1.01 to 1.11)1.01 (1.00 to 1.01)0.99 (0.98 to 0.99)1.16 (1.13 to 1.20)0.98 (0.96 to 1.01)1.02 (0.96 to 1.09)1.00 (0.98 to 1.01)
  46–601.05 (1.00 to 1.10)1.03 (1.02 to 1.04)0.97 (0.96 to 0.98)1.25 (1.21 to 1.29)0.81 (0.79 to 0.84)1.07 (1.00 to 1.15)0.99 (0.97 to 1.00)
  >601.02 (0.97 to 1.08)1.07 (1.06 to 1.08)0.95 (0.94 to 0.96)1.20 (1.16 to 1.25)0.68 (0.66 to 0.70)1.11 (1.04 to 1.19)0.96 (0.94 to 0.97)
Race/ethnicity
  White1.001.001.001.001.001.001.00
  Black0.99 (0.96 to 1.01)0.97 (0.96 to 0.97)1.01 (1.01 to 1.02)1.10 (1.08 to 1.12)1.14 (1.12 to 1.16)1.03 (1.01 to 1.07)1.03 (1.02 to 1.04)
  Hispanic0.96 (0.93 to 0.99)0.98 (0.97 to 0.98)1.03 (1.02 to 1.03)0.93 (0.91 to 0.95)0.94 (0.92 to 0.97)0.97 (0.93 to 1.01)1.04 (1.02 to 1.05)
  Other0.92 (0.88 to 0.96)0.93 (0.92 to 0.94)1.07 (1.06 to 1.08)1.12 (1.09 to 1.15)0.91 (0.88 to 0.93)1.16 (1.10 to 1.21)1.02 (1.00 to 1.04)
Sex
  Female1.001.001.001.001.001.001.00
  Male0.93 (0.91 to 0.95)1.01 (1.01 to 1.02)1.00 (1.00 to 1.00)0.95 (0.94 to 0.96)0.83 (0.81 to 0.84)0.98 (0.96 to 1.01)0.99 (0.99 to 1.00)
Cause of ESRDa
  Hypertension1.001.001.001.001.001.001.00
  Diabetes0.91 (0.88 to 0.93)1.00 (0.99 to 1.00)1.02 (1.01 to 1.02)0.98 (0.96 to 0.99)0.77 (0.75 to 0.79)0.98 (0.95 to 1.01)0.98 (0.97 to 0.99)
  GN1.04 (1.01 to 1.07)0.98 (0.97 to 0.98)1.04 (1.03 to 1.05)0.85 (0.83 to 0.87)0.93 (0.90 to 0.95)0.99 (0.95 to 1.04)0.99 (0.98 to 1.01)
  Other0.99 (0.97 to 1.02)0.99 (0.99 to 1.00)0.99 (0.98 to 0.99)1.10 (1.08 to 1.12)1.32 (1.29 to 1.34)0.93 (0.90 to 0.96)0.99 (0.98 to 1.00)
Body mass index, kg/m2
  <18.51.001.001.001.001.001.001.00
  18.5–24.90.93 (0.91 to 0.95)1.00 (1.00 to 1.01)1.02 (1.02 to 1.02)0.87 (0.86 to 0.89)0.89 (0.87 to 0.90)0.93 (0.91 to 0.96)1.00 (0.99 to 1.01)
  25–29.91.02 (0.96 to 1.09)1.03 (1.01 to 1.04)0.98 (0.97 to 0.99)1.07 (1.03 to 1.06)0.91 (0.87 to 0.95)1.06 (0.98 to 1.15)0.98 (0.96 to 1.00)
  ≥300.85 (0.83 to 0.87)1.03 (1.02 to 1.03)1.00 (1.00 to 1.01)0.88 (0.86 to 0.89)0.81 (0.80 to 0.82)0.89 (0.87 to 0.92)0.99 (0.98 to 1.00)
Panel reactive antibodies, %
  01.001.001.001.001.001.001.00
  1–200.99 (0.94 to 1.03)0.94 (0.93 to 0.95)1.08 (1.07 to 1.09)0.83 (0.81 to 0.85)1.26 (1.21 to 1.31)0.99 (0.95 to 1.04)0.98 (0.97 to 1.00)
  21–801.31 (1.27 to 1.35)0.92 (0.92 to 0.93)1.01 (1.01 to 1.02)1.06 (1.04 to 1.08)2.79 (2.71 to 2.88)0.97 (0.94 to 1.01)1.02 (1.01 to 1.04)
  >802.43 (2.33 to 2.53)0.75 (0.74 to 0.75)0.86 (0.85 to 0.87)1.48 (1.44 to 1.51)12.17 (11.74 to 12.61)1.04 (0.98 to 1.09)0.97 (0.94 to 0.99)
Donor characteristics
Age, yr
  ≤251.001.001.001.001.001.001.00
  26–451.13 (1.10 to 1.16)0.88 (0.86 to 0.90)0.98 (0.96 to 1.00)1.31 (1.26 to 1.36)0.98 (0.95 to 1.01)1.14 (1.05 to 1.24)1.59 (1.48 to 1.70)
  46–601.19 (1.15 to 1.23)1.25 (1.22 to 1.28)0.73 (0.71 to 0.75)1.52 (1.47 to 1.57)0.93 (0.90 to 0.97)1.77 (1.63 to 1.90)1.26 (1.15 to 1.38)
  >601.01 (0.96 to 1.06)1.80 (1.75 to 1.85)0.54 (0.52 to 0.55)1.84 (1.76 to 1.91)0.73 (0.69 to 0.76)2.16 (1.99 to 2.35)0.71 (0.63 to 0.79)
Race/ethnicity
  White1.001.001.001.001.001.001.00
  Black0.91 (0.88 to 0.94)1.01 (0.99 to 1.03)0.91 (0.89 to 0.93)1.44 (1.38 to 1.50)1.13 (1.09 to 1.16)0.82 (0.76 to 0.88)1.27 (1.17 to 1.38)
  Hispanic0.81 (0.78 to 0.84)0.93 (0.91 to 0.95)0.90 (0.87 to 0.92)1.31 (1.27 to 1.36)1.23 (1.19 to 1.27)0.95 (0.89 to 1.01)1.71 (1.61 to 1.82)
  Other1.21 (1.14 to 1.29)1.08 (1.12 to 1.14)0.83 (0.79 to 0.88)1.56 (1.48 to 1.64)1.05 (0.99 to 1.12)1.69 (1.58 to 1.81)1.26 (1.14 to 1.40)
Sex
  Female1.001.001.001.001.001.001.00
  Male1.01 (0.99 to 1.03)0.89 (0.87 to 0.91)1.12 (1.10 to 1.14)1.04 (1.02 to 1.07)0.96 (0.93 to 0.98)0.82 (0.78 to 0.86)1.03 (0.98 to 1.08)
Creatinine, mg/dl
  <1.01.001.001.001.001.001.001.00
  1.0–1.50.92 (0.89 to 0.94)0.92 (0.91 to 0.94)1.07 (1.05 to 1.09)0.88 (0.85 to 0.90)1.10 (1.07 to 1.13)0.87 (0.82 to 0.92)1.06 (0.99 to 1.12)
  >1.50.57 (0.55 to 0.59)1.85 (1.81 to 1.89)0.63 (0.62 to 0.65)0.78 (0.75 to 0.80)0.83 (0.80 to 0.85)0.78 (0.74 to 0.83)0.60 (0.55 to 0.65)
Hypertension
  Yes0.81 (0.79 to 0.84)1.27 (1.25 to 1.29)0.96 (0.94 to 0.98)0.83 (0.81 to 0.85)0.68 (0.66 to 0.70)0.71 (0.68 to 0.75)0.49 (0.46 to 0.53)
  No1.001.001.001.001.001.001.00
Diabetes
  Yes0.74 (0.71 to 0.78)1.48 (1.44 to 1.52)0.70 (0.68 to 0.72)1.03 (1.00 to 1.07)0.89 (0.86 to 0.93)0.66 (0.61 to 0.71)0.84 (0.76 to 0.93)
  No1.001.001.001.001.001.001.00
Cerebrovascular accident
  Yes1.14 (1.11 to 1.17)1.11 (1.09 to 1.13)0.90 (0.88 to 0.92)1.13 (1.10 to 1.16)1.21 (1.17 to 1.24)1.32 (1.26 to 1.38)0.88 (0.83 to 0.94)
  No1.001.001.001.001.001.001.00
Cardiac death
  Yes0.84 (0.81 to 0.86)1.79 (1.75 to 1.83)0.63 (0.62 to 0.64)0.87 (0.85 to 0.90)1.02 (0.98 to 1.05)1.19 (1.10 to 1.27)0.60 (0.56 to 0.64)
  No1.001.001.001.001.001.001.00
Number of offers (quintiles)
  0–1821.98 (1.67 to 2.35)1.07 (1.03 to 1.10)0.85 (0.83 to 0.87)1.75 (1.61 to 1.90)2.56 (2.36 to 2.78)1.32 (1.24 to 1.41)0.86 (0.81 to 0.91)
  183–5751.33 (1.13 to 1.58)1.11 (1.07 to 1.14)0.92 (0.89 to 0.95)1.24 (1.14 to 1.35)1.09 (1.00 to 1.18)1.07 (0.99 to 1.14)0.87 (0.82 to 0.92)
  576–13761.26 (1.07 to 1.48)1.09 (1.05 to 1.13)0.92 (0.90 to 0.95)1.35 (1.24 to 1.47)1.01 (0.92 to 1.11)1.13 (1.06 to 1.22)0.91 (0.86 to 0.96)
  1377–36481.27 (1.09 to 1.47)1.02 (0.99 to 1.05)0.97 (0.94 to 0.99)1.38 (1.28 to 1.49)1.08 (1.00 to 1.17)1.16 (1.08 to 1.24)0.96 (0.91 to 1.01)
  ≥36491.001.001.001.001.001.001.00
Transplant center characteristics
Volume
  Per 100 transplants1.10 (1.10 to 1.11)1.07 (1.07 to 1.07)0.92 (0.92 to 0.92)1.19 (1.18 to 1.19)0.96 (0.95 to 0.97)1.02 (1.01 to 1.03)0.97 (0.97 to 0.98)
  Living transplants0.99 (0.99 to 0.99)1.00 (1.00 to 1.00)1.00 (1.00 to 1.00)0.99 (0.99 to 0.99)1.00 (1.00 to 1.00)0.99 (0.99 to 0.99)1.00 (1.00 to 1.00)
Minority waitlisted patients
  Per 10% black0.83 (0.82 to 0.84)0.99 (0.99 to 0.99)1.01 (1.01 to 1.02)1.04 (1.03 to 1.05)1.05 (1.04 to 1.06)0.97 (0.95 to 0.99)0.97 (0.97 to 0.98)
  Per 10% Hispanic0.81 (0.80 to 0.82)0.96 (0.96 to 0.97)1.03 (1.03 to 1.04)1.04 (1.03 to 1.05)1.02 (1.01 to 1.03)0.97 (0.96 to 0.99)1.01 (1.00 to 1.01)
  • Data are displayed as odds ratios (95% confidence intervals).