Table 2.

List of the 20 proteins that were significantly associated with eGFR decline in both the PIVUS and ULSAM studies

Protein Name (in Order of Significance)AcronymProtein Identification Number
TNF-related apoptosis-inducing ligand receptor 2TRAIL-R2aO14763
CD40L receptorCD40P29965
Soluble TNF receptor 1sTNFR1aP19438
Placenta growth factorPlGFaP49763
Urokinase plasminogen activator surface receptorU-PARaQ03405
Growth/differentiation factor 15GDF15aQ99988
Macrophage colony-stimulating factor 1CSF-1P21583
Fatty acid-binding protein 4FABP4aP15090
Cathepsin DCTSDP07339
Kallikrein 11hK11aQ9UBX7
C-C motif chemokine 3CCL3P10147
Proteinase-activated receptor 1PAR-1aP25116
Cathepsin LCTSLP07711
Chitinase 3-like protein 1CHI3LIP36222
TNF receptor 2sTNFR2aP20333
Fibroblast growth factor 23FGF-23aQ9GZV9
  • PIVUS, the Prospective Investigation of the Vasculature in Uppsala Seniors Study; ULSAM, the Uppsala Longitudinal Study of Adult Men.

  • a Proteins also associated with CKD incidence.