Table 3.

Relationship between indicated exposure at index visit and subsequent decline of >50% in GFR or initiation of RRT, n=751

ExposureNo.No. (%) with EventRegression ModelaRelative Time95% Confidence Interval
Urine protein-to-creatinine, mg/mg
 <0.228725 (9)GG (3.553,1.086,0.690)1 (reference)
 0.2–2.0363112 (31)GG (2.393,1.086,0.690)0.310.21 to 0.47
 >2.010165 (64)GG (0.974,1.086,0.690)0.080.04 to 0.13
Urine albumin-to-creatinineb, mg/g
 <5628731 (11)GG (3.391,1.024,0.784)1 (reference)
 56–1333363104 (29)GG (2.428,1.024,0.784)0.380.26 to 0.55
 >133310167 (66)GG (1.031,1.024,0.784)0.090.06 to 0.15
Urine nonalbumin-to-creatinineb, mg/g
 <11828725 (9)GG (3.593,1.233,0.507)1 (reference)
 118–715363112 (31)GG (2.411,1.233,0.507)0.310.20 to 0.46
 >71510165 (64)GG (0.936,1.233,0.507)0.070.04 to 0.12
  • GG, generalized gamma.

  • a Includes the location, scale, and shape parameters of the regression model.

  • b Cutoffs for urine albumin-to-creatinine and urine nonalbumin-to-creatinine were chosen to yield same sample sizes as determined by urine protein-to-creatinine cutoffs of 0.2 and 2.0.