Table 4.

Relationship between indicated exposure at index visit and subsequent decline of >50% in GFR or initiation of RRT, n=751

ExposureNo.No. (%) with EventRegression ModelaRelative Time95% Confidence Interval
Urine protein-to-creatinineb, mg/mg
 <0.13922017 (8)GG (3.721,0.935,0.991)1 (reference)
 0.139–0.63027146 (17)GG (3.043,0.935,0.991)0.510.30 to 0.86
 >0.630260139 (53)GG (1.662,0.935,0.991)0.130.07 to 0.22
Urine albumin-to-creatinine, mg/g
 <3022023 (10)GG (3.469,0.932,0.977)1 (reference)
 30–30027146 (17)GG (3.001,0.932,0.977)0.630.40 to 1.00
 >300260133 (51)GG (1.663,0.932,0.977)0.160.10 to 0.26
Urine nonalbumin-to-creatinineb, mg/g
 <8622018 (8)GG (3.913,0.336,3.328)1 (reference)
 86–27327149 (18)GG (3.166,0.336,3.328)0.470.27 to 0.84
 >273260135 (52)GG (2.065,0.336,3.328)0.160.09 to 0.28
  • GG, generalized gamma.

  • a Includes the location, scale, and shape parameters of the regression model.

  • b Cutoffs for urine protein-to-creatinine and urine nonalbumin-to-creatinine were chosen to yield same sample sizes as determined by urine albumin-to-creatinine cutoffs of 30 and 300.