Table 1.

Clinical characteristics and laboratory parameters at 1 yr after kidney transplantation in the study population according to the serum phosphorus levels at 1 yr after transplantation

ParametersSerum Phosphorus Levels at 1 yr after TransplantationP Valuea
<2.5 mg/dl (n=115)2.5–2.99 mg/dl (n=351)3.0–3.49 mg/dl (n=690)3.5–3.99 mg/dl (n=848)4.0–4.49 mg/dl (n=523)4.5–4.99 mg/dl (n=190)≥5.0 mg/dl (n=69)
Age, yr43.4±9.741.6±10.741.5±11.141.5±11.642.2±11.842.4±12.239.0±12.10.20
Men, %70.4%65.5%62.2%58.0%53.7%54.2%50.7%<0.001
BMI, kg/m223.1±3.123.0±3.422.5±3.122.0±3.022.1±3.121.7±3.122.0±3.0<0.001
Diabetes, %b24.3%23.7%24.3%26.9%27.9%31.1%23.2%0.03
Dialysis duration, moc56.6 (17.8, 87.4)24.5 (6.3, 70.3)20.0 (5.0, 50.7)15.3 (4.3, 42.5)14.7 (3.0, 36.1)19.0 (3.9, 52.6)21.2 (5.6, 40.9)<0.001
Living donor, %53.6%71.3%71.5%80.8%75.7%75.8%66.2%<0.001
HLA mismatch, n3.0±1.83.2±1.73.1±1.73.1±1.73.0±1.73.1±1.73.3±1.70.45
Tacrolimus %53.9%48.4%41.9%37.5%37.7%32.1%47.8%<0.001
Cyclosporin, %15.7%28.2%34.8%45.3%49.1%56.8%42.0%
Acute rejection, %15.7%21.1%22.9%19.3%23.9%22.6%30.4%0.10
BKVN, %2.6%1.1%2.0%2.1%1.7%2.6%2.9%0.87
Donor age, yr39.6±11.740.4±11.438.7±12.039.6±12.438.6±12.838.5±11.834.0±12.50.003
Male donor sex, %63.4%58.6%58.8%54.5%57.5%61.8%50.8%0.29
eGFR, ml/min per 1.73 m265.4±19.365.1±17.863.1±15.661.9±16.761.5±15.859.5±17.447.5±25.7d<0.001
Creatinine, mg/dl1.22±0.421.21±0.361.22±0.331.25±0.461.24±0.471.31±0.622.97±3.70d<0.001
Ca, mg/dl10.0±0.9d9.6±0.89.5±0.69.3±0.59.3±0.59.3±0.59.2±0.5<0.001
Corrected Cae10.1±0.9d9.7±0.89.5±0.69.4±0.59.4±0.59.4±0.59.4±0.6<0.001
Ca-P product21.0±3.9d26.3±2.4d30.4±2.1d34.5±2.2d38.9±2.3d43.0±2.6d49.9±5.6d<0.001
Albumin, g/dl4.0±0.54.1±0.44.1±0.44.1±0.34.1±0.44.1±0.43.9±0.6<0.001
Hemoglobin, g/dl13.5±2.313.7±1.913.6±2.013.3±1.913.1±1.812.8±1.812.2±2.3<0.001
T.Chol, mg/dl175.6±32.9173.5±32.7179.3±32.0180.5±32.8182.5±33.7182.9±36.0174.7±41.10.002
iPTH, ng/pg246.3±211.9d159.1±203.768.8±56.364.0±46.956.5±63.765.0±68.076.3±129.6<0.001
  • Most continuous values are expressed as the mean±SD, unless stipulated otherwise. BMI, body mass index; HLA, human leukocyte antigen; BKVN, BK virus nephropathy; Ca, calcium; Ca-P, calcium-phosphorus; T.Chol, total cholesterol; iPTH, intact parathyroid hormone.

  • a The chi-squared test was used for categoric variables, whereas continuous variables were compared using one-way ANOVA, as appropriate.

  • b Diabetes mellitus including new onset diabetes after transplantation.

  • c Dialysis duration is expressed as median (25th, 75th percentile).

  • d Post hoc analysis indicated that this group differed significantly from all other groups.

  • e Corrected calcium level was calculated according to the following equation: corrected calcium = measured calcium + 0.8 × (4.0 − serum albumin in g/dl).