Table 2.

Relative hazards for death-censored graft loss using donor/recipient absolute weight difference and donor/recipient sex pairing

Donor-Recipient PairingHR (95% CI)
Weight-unadjusted
 >30 kg (D>R)1.00 (0.96 to 1.05)
 10–30 kg (D>R)0.97 (0.93 to 1.00)
 <10 kg (D=R)Ref
 10–30 kg (D<R)1.11 (1.07 to 1.15)
 >30 kg (D<R)1.28 (1.22 to 1.34)
Weight-adjusteda
 >30 kg (D>R)1.00 (0.94 to 1.04)
 10–30 kg (D>R)0.97 (0.93 to 1.01)
 <10 kg (D=R)Ref
 10–30 kg (D<R)1.10 (1.05 to 1.13)
 >30 kg (D<R)1.22 (1.16 to 1.28)
Sex-unadjusted
 MDMRRef
 FDFR1.12 (1.08 to 1.16)
 MDFR1.00 (0.96 to 1.04)
 FDMR1.22 (1.18 to 1.27)
Sex-adjustedb
 MDMRRef
 FDFR1.08 (1.02 to 1.14)
 MDFR1.08 (1.03 to 1.13)
 FDMR1.10 (1.05 to 1.15)
  • HR, hazard ratio; 95% CI, 95% confidence interval; D>R, donor greater than recipient; D=R, donor equal to recipient; Ref, reference; D<R, donor less than recipient; MDMR, male donor/male recipient; FDFR, female donor/female recipient; MDFR, male donor/female recipient; FDMR, female donor/male recipient.

  • a Adjusted for: donor factors: type (expanded criteria donor versus standard criteria donor), donation by cardiac death, sex, race, height, diabetes status, hepatitis C; surgical & immunologic factors: number of human leukocyte antigen mismatches, peak panel reactive antibody, induction therapy, cold ischemia time; recipient factors: diabetes, age, cause of ESRD, sex, race, height, previous kidney transplant, dialysis vintage.

  • b Adjusted for: donor factors: type (expanded criteria donor versus standard criteria donor), donation by cardiac death, race, height, weight, diabetes status, hepatitis C; surgical & immunologic factors: number of human leukocyte antigen mismatches, peak panel reactive antibody, induction therapy, cold ischemia time; recipient factors: diabetes, age, cause of ESRD, race, height, weight, previous kidney transplant, dialysis vintage.