Table 3.

Sensitivity analysis of Cox proportional hazard models of all-cause and cause-specific mortality by mean corpuscular volume category

All-Cause MortalityCVD MortalityInfection Mortality
Hazard Ratio (95% CI)P ValueHazard Ratio (95% CI)P ValueHazard Ratio (95% CI)P Value
Model S1, n=1439
 MCV1.84 (1.35 to 2.51)<0.0012.06 (1.02 to 4.12)0.041.78 (1.14 to 2.79)0.01
Model S2, n=417
 MCV3.35 (1.76 to 6.37)<0.0012.92 (1.57 to 5.42)0.0013.44 (1.35 to 8.74)<0.01
 Ferritin1.00 (0.99 to 1.00)0.851.00 (0.99 to 1.00)0.960.99 (0.99 to 1.00)0.19
 Transferrin saturation0.16 (0.01 to 1.59)0.120.37 (0.03 to 3.94)0.420.68 (0.01 to 29.10)0.85
  • The referent group for all models is MCV below the median of 90.8. Model S1: adjusted for strata by quintiles on the basis of propensity scores in addition to all of the covariates in model 5 in Table 2. Model S2: adjusted for ferritin and transferrin saturation in addition to all of the variables in model 5 in Table 2. CVD, cardiovascular disease; 95% CI, 95% confidence interval; MCV, mean corpuscular volume.