Patient-reported measures for HCV+ versus HCV− patients (DOPPS phases 1–5, 1996–2015): Logistic regression models
| Outcome Measure (Lower=Better) | Outcome Prevalence, % | Unadjusted Odds Ratio (95% CI)a | Adjusted Odds Ratio (95% CI)b |
|---|---|---|---|
| Depressionc | 44.1 | 1.28 (1.17 to 1.40)d | 1.27 (1.16 to 1.40)d |
| Prurituse | 40.6 | 1.24 (1.16 to 1.33)d | 1.27 (1.18 to 1.36)d |
| Lack of appetitef | 23.2 | 1.25 (1.16 to 1.35)d | 1.22 (1.12 to 1.32)d |
HCV+, hepatitis C virus-positive; HCV−, hepatitis C virus-negative; DOPPS, Dialysis Outcomes and Practice Patterns Study; 95% CI, 95% confidence interval.
↵a Adjusted for DOPPS country (United States black and nonblack patients considered separately)and phase and accounting for facility clustering.
↵b Additionally adjusted for age, sex, time on dialysis, 13 summary comorbidities and hepatitis B infection, and albumin, phosphorus, and creatinine levels.
↵c Odds ratio from a logistic model for a Center for Epidemiologic Studies Short Depression Scale (CES-D-10) score ≥10 (versus <10) for HCV+ versus HCV− patients (n=34,035 patients); not collected in DOPPS phase 1 (1996–2001).
↵d P<0.05.
↵e Odds ratio for moderately to extremely bothered by itchiness for HCV+ versus HCV− patients (n=52,469 patients).
↵f Odds ratio for moderately to extremely bothered by lack of appetite for HCV+ versus HCV− patients (n=52,185 patients).