Table 6.

Patient-reported measures for HCV+ versus HCV− patients (DOPPS phases 1–5, 1996–2015): Logistic regression models

Outcome Measure (Lower=Better)Outcome Prevalence, %Unadjusted Odds Ratio (95% CI)aAdjusted Odds Ratio (95% CI)b
Depressionc44.11.28 (1.17 to 1.40)d1.27 (1.16 to 1.40)d
Prurituse40.61.24 (1.16 to 1.33)d1.27 (1.18 to 1.36)d
Lack of appetitef23.21.25 (1.16 to 1.35)d1.22 (1.12 to 1.32)d
  • HCV+, hepatitis C virus-positive; HCV−, hepatitis C virus-negative; DOPPS, Dialysis Outcomes and Practice Patterns Study; 95% CI, 95% confidence interval.

  • a Adjusted for DOPPS country (United States black and nonblack patients considered separately)and phase and accounting for facility clustering.

  • b Additionally adjusted for age, sex, time on dialysis, 13 summary comorbidities and hepatitis B infection, and albumin, phosphorus, and creatinine levels.

  • c Odds ratio from a logistic model for a Center for Epidemiologic Studies Short Depression Scale (CES-D-10) score ≥10 (versus <10) for HCV+ versus HCV− patients (n=34,035 patients); not collected in DOPPS phase 1 (1996–2001).

  • d P<0.05.

  • e Odds ratio for moderately to extremely bothered by itchiness for HCV+ versus HCV− patients (n=52,469 patients).

  • f Odds ratio for moderately to extremely bothered by lack of appetite for HCV+ versus HCV− patients (n=52,185 patients).