Table 2.

Cardiovascular measures at study entry

Measurements and ClassificationsStage 3aStage 3bStage 4Stage 5All
Systolic office BP
 Millimeters of mercury112 (15)114 (15)111 (15)117 (15)112 (15)
 SDS0.60 (1.16)0.92 (1.39)0.67 (1.34)1.27 (1.39)0.79 (1.36)
Diastolic office BP
 Millimeters of mercury70 (11)70 (13)68 (12)74 (12)69 (12)
 SDS0.67 (0.94)0.71 (1.12)0.59 (1.07)1.10 (1.08)0.67 (1.09)
24-h Mean arterial pressure
 Millimeters of mercury88.2 (8.8)85.0 (9.5)85.0 (10.3)90.1 (12.0)85.6 (10.1)
 SDS1.16 (1.61)0.71 (1.65)0.74 (1.73)1.59 (2.03)0.82 (1.73)
Confirmed normotension, N (%)25 (61.0)114 (63.3)189 (66.3)13 (34.2)341 (62.7)
White coat hypertension, N (%)6 (14.6)22 (12.2)26 (9.1)7 (18.4)61 (11.2)
Masked hypertension, N (%)7 (17.1)21 (11.7)43 (15.1)8 (21.1)79 (14.5)
Confirmed hypertension, N (%)3 (7.3)23 (12.8)27 (9.5)10 (26.3)63 (11.6)
No. of antihypertensive drugs1.2 (1.3)1.3 (1.1)1.6 (1.3)1.6 (1.5)1.4 (1.3)
Normotension without treatment, N (%)13 (31.7)35 (19.4)58 (20.4)6 (15.8)112 (20.6)
Controlled hypertension, N (%)18 (43.9)101 (56.1)157 (55.1)14 (36.8)290 (53.3)
Uncontrolled hypertension, N (%)10 (24.4)44 (24.4)70 (24.8)18 (47.4)142 (26.1)
LV mass index, g/m2.730.6 (8.1)35.3 (12.0)37.9 (11.5)40.8 (16.6)36.8 (12.1)
LV hypertrophy, N (%)5 (10.6)56 (28.1)126 (37.5)24 (48.0)211 (33.4)
 Eccentric0 (0.0)19 (9.5)49 (14.6)7 (14.0)75 (11.9)
 Concentric5 (10.6)37 (18.6)77 (22.9)17 (34.0)136 (21.5)
Concentric LV remodeling, N (%)18 (38.3)61 (30.7)74 (22.0)11 (22.0)164 (25.9)
Carotid intima-media thickness
 Millimeters0.46 (0.06)0.44 (0.06)0.45 (0.06)0.46 (0.07)0.45 (0.06)
 SDS1.81 (1.36)1.39 (1.36)1.66 (1.46)1.87 (1.77)1.60 (1.45)
Elevated carotid intima-media thickness, N (%)20 (40.8)73 (34.0)162 (46.0)22 (44.0)277 (41.6%)
Pulse wave velocity
 Meters per second5.12 (1.01)4.91 (0.79)4.85 (0.82)5.07 (0.88)4.90 (0.83)
 SDS0.37 (1.50)0.23 (1.51)0.31 (1.77)0.79 (1.67)0.33 (1.66)
Elevated pulse wave velocity, N (%)9 (19.1)37 (17.3)76 (21.5)10 (20.4)133 (20.1)
  • Values are presented as mean (SD) unless otherwise indicated. Ambulatory BP monitoring–derived data are on the basis of 545 patients. SDS, SD score; LV, left ventricular.