Table 1.

Population characteristics at baseline and follow-up in the Renal Iohexol Clearance Survey in Tromsø 6 Follow-Up Study

CharacteristicsBaselineFollow-upP Value
N (%)12461246
Men, n (%)620 (49.8)620 (49.8)
Age, yr57.9 (3.9)63.5 (4.0)
Height, cm170.9 (8.6)170.7 (8.7)<0.001
Body weight, kg79.1 (13.6)78.9 (13.9)0.33
Body mass index, kg/m227.0 (3.7)27.0 (3.9)0.45
Current smoker, n (%)225 (18.2)162 (13.1)0.01
Use of alcohol more than once a week, n (%)358 (28.7)420 (33.7)<0.001
LDL cholesterol, mg/dl141.3 (32.8)138.6 (34.8)0.01
HDL cholesterol, mg/dl59.9 (17.8)63.3 (18.2)<0.001
Fasting glucose, mg/dl95.4 (8.3)98.0 (8.8)<0.001
Hemoglobin A1c, %5.51 (0.33)5.59 (0.29)<0.001
Fasting triglycerides, mg/dl88.5 (61.9–123.9)88.5 (71.0–115.0)0.09
Urinary albumin-to-creatinine ratio, mg/g1.85 (0.89–4.46)2.96 (0.89–5.02)<0.001
Conventional systolic BP, mmHg128.7 (17.3)130.4 (16.9)<0.001
Conventional diastolic BP, mmHg83.2 (9.7)81.9 (9.2)<0.001
Ambulatory systolic BP, mmHg129.5 (13.0)
Ambulatory diastolic BP, mmHg82.0 (8.7)
Antihypertensive medication, n (%)206 (16.6)373 (29.9)<0.001
 ACE inhibitor21 (1.7)40 (3.2)<0.001
 A2 blocker96 (7.7)183 (15)<0.001
Measured GFR,a ml/min103.4 (19.4)98.1 (19.5)<0.001
Measured GFR,a ml/min per 1.73 m293.6 (14.1)88.9 (14.2)<0.001
  • Estimates are given as the means (SDs), medians (interquartile ranges), or numbers (percentages). Not including the Renal Iohexol Clearance Survey in Tromsø 6 Follow-Up Study participants with diabetes at baseline or follow-up or participants with albuminuria at baseline. ACE, angiotensin-converting enzyme.

  • a GFR was measured by plasma iohexol clearance.