Table 2.

Unadjusted competing risk regression for ESRD showing concepts with q values <0.05 (top 10 positive and negative predictors shown; full results are in Supplemental Table 1)

UMLS CUIMost Common Phrase (Three Most Correlated Phrases [Φ-Coefficient])HR [95% CI]q ValuePrevalence (%)
Top 10 positive predictors (HR>1) by q value (lowest to highest)
 C0022661Chronic renal insufficiency (CKD [0.77], chronic disease [0.71], renal insufficiency [0.66])5.07 [3.52 to 7.31]<0.00115.9
 C0022658Nephropathy (renal impairment [0.89], renal insufficiency [0.81], CKD [0.7])3.45 [2.44 to 4.89]<0.00117.2
 C0917873Dialysisa (hemodialysis [0.38], ESRD [0.34], uremia [0.3])4.64 [3.01 to 7.17]<0.0015.6
 C0011946Dialysisa (hemodialysis [0.37], ESRD [0.34], uremia [0.3])4.64 [3.01 to 7.16]<0.0015.6
 C0403447CKD (chronic disease [0.92], renal impairment [0.78], chronic renal insufficiency [0.77])3.36 [2.38 to 4.73]<0.00121.9
 C0035078Renal insufficiency (renal impairment [0.91], nephropathy [0.81], chronic renal insufficiency [0.66])3.55 [2.47 to 5.11]<0.00125.4
 C0546817Volume overload (diuresis [0.61], diuresed [0.6], BNP [0.52])3.85 [2.54 to 5.84]<0.0017.2
 C0020223Hydralazine (hydralazine HCl [0.65], labetalol [0.33], CK-MB [0.29])4.01 [2.54 to 6.33]<0.0014.4
 C0699992Lasix (furosemide [0.74], sulfonamide [0.61], furosemide 40 mg [0.51])2.82 [2.00 to 3.97]<0.00119
 C0016860Furosemide (sulfonamide [0.8], lasix [0.74], furosemide 40 mg [0.66])2.84 [1.99 to 4.07]<0.00113.6
Top 10 negative predictors (HR<1) by q value (lowest to highest)
 C0227391Sigmoid (descending colon [0.43], transverse colon [0.36], large bowel [0.33])<0.01 [<0.01 to <0.01]<0.0016.6
 C1299496Radiology report (anion gap [0.14], 3.9 [0.14], pigment [0.13])<0.01 [<0.01 to <0.01]<0.0014.1
 C0231953Lung volumes (FRC [0.46], diffusing capacity [0.45], atelectasis [0.36])<0.01 [<0.01 to <0.01]<0.0014.6
 C0014672Equipment (procedure/site [0.42], knowledge deficit [0.4], nursing care [0.36])<0.01 [<0.01 to <0.01]<0.0014.7
 C0221103Suppression (acid [0.24], suppressed [0.17], bone marrow [0.15])<0.01 [<0.01 to <0.01]<0.0014.1
 C0439181Suppression (acid [0.24], suppressed [0.17], bone marrow [0.15])<0.01 [<0.01 to <0.01]<0.0014.1
 C0086930Risk assessment (homicidal ideation [0.73], abnormal movements [0.65], suicidal ideation [0.65])<0.01 [<0.01 to <0.01]<0.0014.5
 C0184924Punch biopsy (punch biopsy [0.99], punch [0.58], suture removal [0.57])<0.01 [<0.01 to <0.01]<0.0013.4
 C0700201Sleep disturbance (fear of falling [0.55], skin problems [0.51], sleep disorder [0.43])<0.01 [<0.01 to <0.01]<0.0014.4
 C0014180Endometrium (myometrium [0.63], right ovary [0.5], right ovary [0.5])<0.01 [<0.01 to <0.01]<0.0013.3
  • UMLS CUI, Unified Medical Language System concept unique identifier; HR, hazard ratio; 95% CI, 95% confidence interval; BNP, B-type Natriuretic Peptide; CK-MB, creatine kinase-myocardial band; FRC, functional residual capacity.

  • a Note that the phrase dialysis maps to two concepts, because we used settings in MetaMap that allowed a phrase to match multiple concepts (instead of choosing only one).