Table 3.

Association of vascular medial fibrosis amount and collagen fiber pattern with postoperative arteriovenous fistula diameter and blood flow rate

Predictor and AVF OutcomeUnadjustedAdjusteda
Difference in Diameter or Blood Flow (95% Confidence Interval)P ValueDifference in Diameter or Blood Flow (95% Confidence Interval)P Value
Arterial medial fibrosis (per 10% greater)
 AVF diameter, mm0.46 (0.13 to 0.79)<0.010.58 (0.27 to 0.89)<0.001
 AVF blood flow, ml/min50 (−24 to 124)0.1985 (19 to 150)0.01
Venous medial fibrosis (per 10% greater)
 AVF diameter, mm−0.04 (−0.45 to 0.37)0.85−0.03 (−0.42 to 0.36)0.88
 AVF blood flow, ml/min16 (78 to 111)0.7418 (−67 to 103)0.67
Arterial fiber orientation (nonparallel versus parallel)
 AVF diameter, mm1.56 (0.13 to 2.98)0.030.98 (−0.49 to 2.45)0.18
 AVF blood flow, ml/min197 (−127 to 522)0.2325 (−278 to 329)0.87
Venous fiber orientation (nonparallel versus parallel)
 AVF diameter, mm0.01 (−1.16 to 1.17)0.99−0.05 (−1.19 to 1.10)0.94
 AVF blood flow, ml/min80 (−183 to 343)0.55−11 (−243 to 222)0.93
  • AVF, arteriovenous fistula.

  • a Adjusted for age, sex, race, congestive heart failure, coronary artery disease, peripheral vascular disease, cerebrovascular disease, hypertension, diabetes, and preoperative vein diameter.