Table 5.

The relation of geriatric impairment with hospitalization

Geriatric Impairment and AuthorsRelation with HospitalizationOutcomeAdjusted for in Multivariate Analysis (if Applicable)
UnivariateMultivariate
HR/RR/OR (95% CI)P ValueHR/RR/OR (95% CI)P Value
Depression
 Lacson et al. (36)<0.0011.13 (1.02 to 1.25)0.02Hospitalization rateAge, sex, race, DM, albumin, creatinine, hemoglobin, calcium, phosphorus, transferrin saturation, SF-36 PCS, SF-36 MCS (two mental health items of interest removed), dialysis vintage
 Lacson et al. (36)<0.0011.20 (1.07 to 1.35)0.002Duration of hospitalizationAge, sex, race, DM, albumin, creatinine, hemoglobin, calcium, phosphorus, transferrin saturation, SF-36 PCS, SF-36 MCS (two mental health items of interest removed), dialysis vintage
Performance
 Churchill et al. (43) (≤80 versus >80)1.63 (—)<0.05Duration of hospitalizationAge, sex, KPS, CVD, DM, albumin, malnutrition, CCr, Kt/V, β2M, country
 Lopez Revuelta et al. (37)1.25 (1.05 to 1.48)a0.011.12 (0.92 to 1.36)a0.51Duration of hospitalizationKPS, CCI, logarithmic time, hospital, SF-36 PCS, SF-36 MCS
Malnutrition
 Churchill et al. (43)0.82 (—)b<0.05Duration of hospitalizationAge, sex, KPS, CVD, DM, albumin, CCr, Kt/V, β2M, country
Frailty
 Bao et al. (19)1.44 (1.26 to 1.66)<0.0011.26 (1.09 to 1.45)<0.001Time to first hospitalizationAge, sex, race, smoking, comorbidities, Medicaid versus other payer, eGFR, albumin, hemoglobin, dialysis modality, erythropoietin use, early nephrology referral
 Johansen et al. (32)1.90 (1.67 to 2.17)<0.051.56 (1.36 to 1.79)<0.05Time to first hospitalization or deathAge, sex, race, BMI, albumin, dialysis modality, comorbidities, employment status, marital status, smoking
 Johansen et al. (32)1.98 (1.41 to 1.87)<0.05Time to first nonvascular–related hospitalization or deathAge, sex, race, BMI, albumin, dialysis modality, comorbidities, employment status, marital status, smoking
  • HR, hazard ratio; RR, relative risk; OR, odds ratio; 95% CI, 95% confidence interval; —, not mentioned; DM, diabetes mellitus; SF-36 PCS, Short–Form (36) Health Survey Physical Component Score; SF-36 MCS, Short–Form (36) Health Survey Mental Component Score; KPS, Karnofsky performance score; CVD, cardiovascular disease; CCr, creatinine clearance; β2M, β2-microglobulin; CCI, Charlson Comorbidity Index.

  • a Risk per increase in score of 10.

  • b Risk per point increase.