Table 1.

Patient characteristics on the basis of performance and self–reported function definitions of frailty

VariableAll, n=762Not Frail, n=330Frail by Self-Report Only, n=192Frail by Performance Only, n=36Frail by Performance and Self-Report, n=204P Value
Age, yr57.1 (14.2)54.1 (14.4)56.4 (12.8)53.1 (14.9)63.5 (13.1)<0.001
Sex, % women40.734.544.838.947.10.02
Race, % black61.561.867.272.253.90.13
Diabetes mellitus50.942.450.558.363.7<0.001
Heart failure29.021.529.227.841.2<0.001
CAD31.421.832.833.345.1<0.001
PAD9.75.87.32.819.6<0.001
CVA or TIA10.27.69.95.615.70.02
Dialysis vintage, yr2.7 (1.2, 5.4)2.9 (1.3, 5.8)2.9 (1.4, 5.3)2.0 (0.7, 4.8)2.4 (1.0, 4.8)0.14
Hemoglobin, g/dl11.5 (1.3)11.6 (1.3)11.6 (1.3)11.4 (1.2)11.4 (1.3)0.13
Serum albumin, g/dl4.0 (0.4)4.1 (0.3)4.0 (0.3)4.0 (0.5)3.9 (0.4)<0.001
CRP, mg/L3.9 (1.5, 9.8)3.1 (1.2, 7.3)3.9 (1.7, 9.8)4.5 (1.8, 16.1)5.1 (1.6, 12.4)0.004
BMI, kg/m228.2 (6.9)27.4 (6.2)28.7 (7.4)27.6 (7.7)29.1 (7.4)0.05
SBP, mmHg151 (23)152 (22)153 (24)152 (19)149 (23)0.28
DBP, mmHg81 (15)83 (15)82 (15)80 (14)76 (15)<0.001
Dialyzing via catheter, %20.716.426.65.625.00.002
  • Values are means±SDs, medians (interquartile ranges), or percentages. CAD, coronary artery disease; PAD, peripheral arterial disease; CVA, cerebrovascular accident; TIA, transient ischemic attack; CRP, C-reactive protein; BMI, body mass index; SBP systolic BP; DBP, diastolic BP.