Table 1.

Baseline characteristics among self-reported European American and African-American participants in the CRIC study

European AmericanAfrican AmericanaP valuef
Variablesn=1523Overall 
n=1490Quartile 1bn=373 Quartile 2cn=368Quartile 3dn=373 Quartile 4en=376
Age58.5±10.9g57.6±10.657.9±11.257.0±10.556.5±10.458.8±10.20.37
Female sex (%)40h51505055510.46
Body mass index (kg/m2)31.3±7.5h33.4±8.233.0±7.433.2±8.134.7±8.932.9±8.40.48
Waist circumference (cm)105.7±17.6h108.0±18.0108.3±17.1107.8±18.7109.9±18.5106.0±17.60.27
eGFR (ml/min per 1.73m2)47.6±17.0h43.8±16.444.5±15.643.5±16.543.3±17.044.0±16.40.65
UACR (mg/g)25.3 (6.2, 212.2)h74.1 (10.9,513.5)75.0 (9.0, 494.4)84.9 (13.1, 554.4)70.5 (9.3, 699.9)68.6 (12.9,407.0)0.77
Co-morbidities (%)
 Diabetes41h52525054500.96
 CVD32h38344639350.61
 Hypertension80h93929292950.10
SBP (mmHg)122.0±18.6h132.9±23.1132.0±22.1132.3±23.6133.5±24.4134.0±22.10.19
DBP (mmHg)69.0±11.4h74.0±13.972.8±14.774.3±12.974.6±13.574.1±14.20.19
Smoking (current, %)10h20212017200.57
Less than high school diploma (%)5h2619272930<0.001
Annual income ≤ $20,000/year (%)18h48404854490.01
Medication use (%)
 Active vitamin D2g436340.99
 Bisphosphonates4h 222220.48
 Binders (non-calcium)0.50.30.30.30.500.65
 Binders (calcium)7666660.88
  • Results are presented as mean±SD, median (interquartile range), or frequencies. CRIC, Chronic Renal Insufficiency Cohort; UACR, urine albumin-to-creatinine ratio; CVD, cardiovascular disease; SBP, systolic blood pressure; DBP, diastolic blood pressure.

  • a African-American data is shown overall and also stratified by quartiles of percentage African ancestry.

  • b Percentage African ancestry <73.6%.

  • c Percentage African ancestry 73.6%–79.6%.

  • d Percentage African ancestry 79.7%–83.8%.

  • e Percentage African ancestry >83.8%.

  • f P for trend across categories of percentage African ancestry among self-reported African Americans; linear test for trend or Wilcoxon rank sum test were used for continuous variables and Cochran–Armitage test for trend was used for categorical variables.

  • g P<0.05 comparing European Americans to African Americans.

  • h P<0.001 comparing European Americans to African Americans.