Table 3.

Measurements of individual kidney volume, hemodynamics, oxygenation, GFR, and overall iothalamate clearance before revascularization or medical therapy alone

ParameterBaselineP Value
Stent STK, n=10Stent CLK, n=10P Value StentMedical STK, n=20Medical CLK, n=20P Value MedicalEH, n=32Stent STK Versus Medical STKEH Versus Stent STKEH Versus Medical STK
CT single–kidney volume total, cm3133.4±43.3166.1±500.0297.5±39.4149.3±44<0.001141.4±43.70.120.580.002
Single–kidney blood flow, ml/min253±123.3377±1590.02227.6±149.7349.9±151.4<0.001399.2±174.20.660.04<0.001
Single-kidney GFR, ml/min30.5±17.743.6±19.70.0224±1239.1±140.0344.3±13.60.600.04<0.001
Single-kidney R2*, 1/s24.7±6.220.9±2.10.0421.6±3.620.8±30.0821±2.40.400.150.99
Cortex R2*, 1/s21.6±618.4±3.20.0119.8±3.918±30.0218.5±2.70.520.090.39
Fractional hypoxia, % R2* >30%22.1±2010.8±60.0214.1±12.610.6±12.30.049.6±70.260.030.19
Stent Versus MedicalEH Versus StentEH Versus Medical
Patient total iothalamate Cl, ml/min74±34.862.6±21.887.9±24.30.800.300.003
  • Data are means±SDs. STK, stenotic kidney; CLK, contralateral kidney; EH, essential hypertension; CT, computed tomography; Cl, clearance.