Table 3.

Studies reporting the association of mild chronic hyponatremia and falls

StudyType of StudyCohort SizeMean PNa ±SD (mEq/L)Fall Risk (OR)
Renneboog et al. (18)Cross-sectional366126±567.43 (95% CI, 7.5 to 607)
Bun et al. (21)Retrospective case control248131.82±2.994.38 (95% CI, 1.33 to 14.46)
Gunathilake et al. (20)Prospective cohort2550135 versus 130a1.32 (95% CI, 1.04 to 1.64)
  • PNa, plasma sodium concentration; OR, odds ratio; 95% CI, 95% confidence interval.

  • a Study compared patients with PNa of 135 versus 130 mEq/L. No mean PNa was provided.