Table 2.

Baseline urinary measures of patients with primary hyperoxaluria without ESRD at or before diagnosis

VariableAll Participants with PHaAdult Participants with PHbAdult Reference Populationc
U[vol], ml/24 h2193 (1605, 3031); 1512740 (2200, 3095); 531319 (1046, 1889); 101
U[ox], mmol/24 h1.64 (1.11, 2.44); 1681.51 (0.89, 1.93); 560.27 (0.22, 0.32); 101
U[Ca], mg/24 h72.9 (43.4, 134.2); 130100.5 (57.5, 177.5); 44191.0 (130.0, 250.0); 101
U[Citrate], mg/24 h398 (197, 698); 120375 (168, 520); 41732 (522, 963); 101
U[Phos], mg/24 h824 (552, 1044); 981012 (636, 1218); 36975 (756, 1183); 101
  • Values are expressed as median (25th, 75th percentiles), followed by number of patients. U[vol], urinary volume; U[ox], urinary oxalate; U[Ca], urinary calcium; U[Citrate], urinary citrate; U[Phos], urinary phosphate; PH, primary hyperoxaluria.

  • a Includes both adults and children and thus normalized to 1.73 m2 body surface area.

  • b Includes only those aged ≥18 years at the time of collection and are not normalized to body surface area.

  • c Values from 101 individuals aged 18–83 years without kidney stones or kidney disease are not normalized to 1.73 m2 body surface area.