Table 3.

Incidence rates and hazard ratios (95% confidence intervals) for primary end points in quartile subgroups stratified according to the levels of urinary potassium excretion

Primary End PointUrinary Potassium Excretion (g/d)Urinary Sodium Excretion (g/d)
Q1 (<1.72)Q2 (1.72–2.32)Q3 (2.33–2.90)Q4 (>2.90)Q1 (<3.81)Q2 (3.81–5.07)Q3 (5.08–6.50)Q4 (>6.50)
Incidence (n)4337322233353333
Incidence rate (per 1000 person years)25.320.918.711.918.719.819.418.2
Crude HR1 (Reference)0.84 (0.54 to 1.31)0.76 (0.48 to 1.20)0.48 (0.29 to 0.80)1 (Reference)1.05 (0.65 to 1.69)1.06 (0.65 to 1.72)0.98 (0.60 to 1.59)
Age- and sex-adjusted HR1 (Reference)0.79 (0.51 to 1.22)0.61 (0.38 to 0.97)0.38 (0.23 to 0.65)1 (Reference)1.14 (0.70 to 1.84)1.01 (0.62 to 1.66)0.86 (0.51 to 1.43)
All adjusted HRa1 (Reference)0.70 (0.44 to 1.13)0.56 (0.33 to 0.95)0.33 (0.18 to 0.62)1 (Reference)1.54 (0.91 to 2.59)1.37 (0.78 to 2.41)1.30 (0.71 to 2.38)
  • Q1, first quartile; Q2, second quartile; Q3, third quartile; Q4, fourth quartile; HR, hazard ratio.

  • a Adjusted by the baseline data, including age, sex, body mass index, hemoglobin A1c, total cholesterol, log triglyceride, log HDL-cholesterol, LDL-cholesterol, systolic BP, renin-angiotensin system inhibitor, hypertension, log urinary albumin excretion rate, eGFR, current smoking, and urinary sodium excretion (or urinary potassium excretion), in the Cox proportional regression analysis.