Table 3.

Frailty Status at Hemodialysis Initiation and Cognitive Function at Hemodialysis Initiation and 1-Year Follow-up

Frailty Status Measured at Hemodialysis Initiation3MS Trail Making Test ATrail Making Test B
Initiation
 Patients (n)323320314
 NonfrailReferenceReferenceReference
 Intermediately frail−1.29 (−3.05 to 0.48)6.12 (−0.94 to 13.18)19.87 (−2.34 to 42.08)
 Frail−2.37 (−4.21 to −0.53)a12.08 (4.73 to 19.43)b33.15 (9.88 to 56.42)a
P for trend0.010.0010.01
1-yr follow-up
 Patients (n)171168161
 NonfrailReferenceReferenceReference
 Intermediately frail−1.74 (−4.16 to 0.69)6.56 (−4.00 to 17.13)1.10 (−28.94 to 31.14)
 Frail−2.80 (−5.37 to −0.24)a8.48 (−2.62 to 19.58)17.42 (−14.29 to 49.14)
P for trend0.030.140.27
  • Data are presented with 95% confidence intervals and are adjusted for sex, age, race, BMI, education, and comorbidity at baseline. 3MS, Modified Mini-Mental State test.

  • a P<0.05.

  • b P<0.001.