Table 2.

Values of AKI markers at inclusion and 24 hours later

MarkerRecovery Group (n=29)Nonrecovery Group (n=28)P Valuea
At inclusion
 FENa (%)0.08 (0.06–0.16)0.19 (0.09–0.51)0.03
 FEUrea (%)16 (10–26)13 (7–27)0.16
 Proteinuria (g/dl)0.08 (0.04–0.11)0.09 (0.05–0.17)0.14
 RI0.66 (0.60–0.72)0.75 (0.67–0.78)0.02
 Plasma NGAL (ng/ml)536 (210–919)1175 (463–1300)0.01
 [TIMP-2]*[IGFBP7] ([ng/ml]2/1000)1.8 (0.6–3.5)3.8 (1.6–9.9)0.01
24h after inclusion
 FENa (%)0.37 (0.18–0.75)0.34 (0.17–1.18)0.61
 FEUrea (%)29 (23–38)b28 (20–37)b0.41
 Proteinuria (g/dl)0.05 (0.04–0.08)0.08 (0.04–0.16)0.16
 RI0.68 (0.63–0.75)0.75 (0.66–0.79)0.02
 Plasma NGAL (ng/ml)378 (203–661)b1300 (512–1300)<0.001
 [TIMP-2]*[IGFBP7] ([ng/ml]2/1000)0.62 (0.30–0.80)b2.2 (0.5–4.2)b0.002
 Kinetic eGFR (ml/min per 1.73 m2)62 (49–87)30 (14–40)<0.001
  • Data are expressed as medians (interquartile ranges). FENa, fractional excretion of sodium; FEUrea, fractional excretion of urea; RI, renal resistive index; NGAL, neutrophil gelatinase–associated lipocalin; [TIMP-2]*[IGFBP7], tissue inhibitor of metalloproteinase-2 and urine insulin-like growth factor–binding protein 7.

  • a P<0.05 for comparison between renal recovery and nonrecovery groups (Mann–Whitney U test).

  • b P<0.05 for comparison between AKI markers at inclusion and 24 hours later (Wilcoxon signed-rank test).