Table 3.

Hazard ratio for the association between rate of kidney function decline and risk of hospitalization and readmission

Risk ModelCKD Progression by eGFR Change Values
No Decline 
in Kidney
Function ( >0)Mild
(Between 0 and −1)Moderate
(Between −1 and −5)Severe (<−5)
Risk of hospitalization111,318 (44.9)36,132 (14.6)74,117 (29.9)26,321 (10.6)
 Model 10.99 (0.96 to 1.02)1.001.22 (1.19 to 1.26)1.32 (1.27 to 1.38)
 Model 20.99 (0.96 to 1.02)1.001.22 (1.19 to 1.26)1.33 (1.28 to 1.39)
 Model 31.06 (1.03 to 1.10)1.001.17 (1.13 to 1.20)1.18 (1.13 to 1.23)
Risk of readmission33,783 (43.8)10,519 (13.6)24,781 (32.1)8137 (10.5)
 Model 10.97 (0.92 to 1.03)1.001.19 (1.13 to 1.26)1.51 (1.42 to 1.62)
 Model 20.97 (0.92 to 1.02)1.001.19 (1.13 to 1.26)1.53 (1.43 to 1.63)
 Model 31.07 (1.01 to 1.13)1.001.12 (1.06 to 1.18)1.29 (1.20 to 1.39)
  • Data are presented as n (%) or hazard ratios (95% confidence intervals). eGFR change values are given in ml/min per 1.73 m2 per year. Model 1 was adjusted for age, race, sex, diabetes mellitus, hypertension, cardiovascular disease, hyperlipidemia, peripheral artery disease, cerebrovascular disease, chronic lung disease, hepatitis C, HIV, and dementia. Model 2 includes covariates in model 1 and initial eGFR. Model 3 includes covariates in model 1 and last eGFR.