Table 1.

Differences in clinical characteristics between PD patients without and with hyponatremia

VariableTotalPatients without HyponatremiaPatients with HyponatremiaP Value
Patients, n (%)476426 (89.5)50 (10.5)
Serum sodium (mmol/L)139.1±3.1139.8±2.4133.1±1.9<0.001
Age (yr)51.9±14.351.4±14.355.9±13.20.04
Men (%)244 (51.4)221(51.9)23 (46.0)0.42
PD duration (mo)26.3 (12.2–49.9)26.3 (12.0–49.2)29.7 (13.0–54.0)0.36
Primary kidney disease, n (%)0.36
 Diabetic nephropathy99 (20.8)86 (20.4)13 (26.0)
 Hypertensive nephropathy 77 (16.1)66 (15.6)11 (22.0)
 Chronic GN 207 (43.6)187 (44.5)20 (40.0)
 Other93 (19.5)87 (19.5)6 (12.0)
Diabetes mellitus, n (%)113 (23.7)97 (22.7)16 (32.7)0.12
Cardiovascular disease, n (%)95 (20.1)86 (20.4)9 (18.0)0.69
Charlson index5 (3–8)5 (3–8)5 (2–8)0.93
Level of education, n (%)0.02
 Elementary school or lower92 (19.3)74 (17.3)18 (36)
 Middle school145 (30.4)133 (31.1)12 (24)
 High school141 (29.6)130 (30.4)11 (22)
 Above high school98 (20.7)89 (21.1)9 (18)
Body mass index (kg/m2)23.0±3.523.0±3.522.9±3.50.97
Systolic BP (mmHg)135.9±18.7135.3±18.8141.9±17.20.02
Diastolic BP (mmHg)82.4±12.382.5±12.682.1±9.40.84
Mean arterial pressure (mmHg)100.3±13.0100.1±13.3102.0±10.30.34
Hemoglobin (g/L)103.3±18.1105.0±17.998.2±19.10.01
Serum albumin (g/L)36.1±5.636.5±5.432.5±5.7<0.001
hsCRP (mg/L)2.96 (0.99–8.70)2.82 (0.91–8.36)5.90 (1.67–12.1)0.03
RRF (ml/min)1.39 (0.00–3.77)1.43 (0.00–3.89)0.63 (0.00–2.93)0.15
Total Kt/V1.91±0.551.88±0.411.92±0.460.51
Total Ccr (ml/min per 1.73 m2 per week)57.9±19.657.8±16.956.5±23.60.64
  • Values are expressed as mean±SD, median (interquartile range), or number (percentage). PD, peritoneal dialysis; hsCRP, high-sensitivity C-reactive protein; RRF, residual renal function; Ccr, creatinine clearance.