Table 3.

Risk factors for hospital mortality in patients with AKI from developed and emerging countries (n=745)

Risk FactorOR (95% CI)
Age 1.03 (1.01 to 1.05)
Emerging country2.32 (1.14 to 4.74)
On vasopressorsa1.84 (1.05 to 3.25)
 In developed countries1.07 (0.42 to 2.71)
 In emerging countries3.51 (1.54 to 7.99)
On mechanical ventilation2.41 (1.23 to 4.73)
APACHE III score1.03 (1.02 to 1.04)
Cumulative fluid balancea1.07 (1.03 to 1.12)
 In developed countries1.12 (1.05 to 1.20)
 In emerging countries0.98 (0.92 to 1.05)
AKI stage 3 with RRT2.03 (1.07 to 3.83)
  • Variables included in the multivariate model were age, race, developing or emerging country, surgery status, Acute Physiology and Chronic Health Evaluation (APACHE) III score, sepsis status, use of vasopressors, mechanical ventilation, starches, RRT, cumulative fluid balance, and significant interaction terms (between country type and vasopressors, between country type and cumulative fluid balance). Area under the receiver-operating characteristic curve (c statistic): 0.87 (95% confidence interval, 0.83 to 0.90); Hosmer–Lemeshow: 0.60. OR, odds ratio; 95% CI, 95% confidence interval.

  • a Vasopressors and cumulative fluid balance presented significant interactions with the developed/emerging status.