Table 3.

Changes in levels of PTH, calcium, and phosphorous from baseline to EAP

Laboratory ParametersCinacalcetVitamin D AnalogsCinacalcet–Vitamin D Analogs
BaselineEAPChangeBaselineEAPChangeTreatment DifferenceP Value
PTH, pg/ml845.7 (431.28)689.0 (480.19)−168.8 (448.60)815.7 (427.90)708.6 (560.78)−97.8 (387.01)−71.0 (−178.7 to 36.6)0.20
Calcium, mg/dl9.5 (0.46)8.7 (0.64)−0.9 (0.74)9.5 (0.54)9.7 (0.54)0.2 (0.59)−1.1 (−1.3 to −0.9)<0.001
Phosphorus, mg/dl5.7 (1.62)5.0 (1.30)−0.7 (1.49)5.8 (1.49)5.6 (1.24)−0.2 (1.42)−0.6 (−1.0 to −0.2)0.002
  • Data are given as the mean (SD) or mean (95% confidence interval). PTH, 1 pg/ml = 0.106 pmol/L; calcium, 1 mg/dl = 0.25 mmol/L; and phosphorus, 1 mg/dl = 0.32 mmol/L. PTH, parathyroid hormone; EAP, efficacy assessment phase.