Table 1.

Patient characteristics and indicators of nutritional status and inflammation in an international European cohort of 37,345 hemodialysis patients

CharacteristicAll
(N=37,345)LTI<10th Percentile, FTI<10th Percentile
(n=1586)LTI<10th Percentile, FTI 10th–90th Percentile
(n=14,608)LTI<10th Percentile, FTI>90th Percentile
(n=1309)LTI 10th–90th Percentile, FTI<10th Percentile
(n=4855)LTI 10th–90th Percentile, FTI 10th–90th Percentile
(n=12,776)LTI 10th–90th Percentile, FTI>90th Percentile
(n=532)LTI>90th Percentile, FTI<10th Percentile
(n=874)LTI>90th Percentile, FTI 10th–90th Percentile
(n=769)LTI>90th Percentile, FTI>90th Percentile
(n=36)P Value
Age (y)62.7±15.262.2±13.061.5±15.158.8±14.663.3±15.664.0±15.459.1±14.067.3±14.665.4±13.561.0±10.0<0.001
Vintage (y)2.8 (0.7–6.1)2.8 (0.5–7.2)3.1 (0.9–6.8)2.4 (0.9–4.9)2.6 (0.4–6.4)2.5 (0.7–5.4)2.1 (0.7–4.5)2.5 (0.5–5.8)2.4 (0.5–4.7)1.5 (0.7–3.5)<0.001
BMI (kg/m2)26.0±5.319.0±1.925.4±3.936.3±5.021.2±2.327.6±4.040.3±4.423.9±3.231.6±4.848.0±6.4<0.001
Men (%)57±4972±4564±4861±4960±4951±5040±4943±4926±4419±40<0.001
Diabetic (%)24±4317±3728±4542±4913±3423±4237±4816±3629±4539±49<0.001
Fat mass (kg)26.1±11.714.0±4.128.8±8.752.0±10.212.7±4.627.0±8.352.3±8.910.2±5.026.5±8.055.4±10.9<0.001
Lean tissue mass (kg)34.4±10.532.0±7.329.7±8.627.4±9.539.6±9.336.9±9.936.2±10.348.8±11.545.4±10.845.2±12.1<0.001
Albumin (g/dl)3.8±0.43.6±0.53.8±0.43.8±0.43.8±0.53.9±0.43.9±0.43.7±0.53.8±0.54.1±0.4<0.001
CRP (mg/L)6.0 (2.5–15)7.8 (2.4–21.6)6.7 (2.8–16.9)9.5 (4–19.7)4.6 (1.6–12.0)5.5 (2.3–12.7)9.9 (5–17.7)5 (2.1–13.2)7.0 (3.1–14.8)10.3 (3.3–16.6)<0.001
Creatinine (mg/dl)7.7±2.56.8±2.07.6±2.47.9±2.57.6±2.48.0±2.68.0±2.77.4±2.47.5±2.68.5±3.0<0.001
Total cholesterol (mg/dl)172.0±44.0164.6±41.9169.6±44.2177.0±46.6167.1±40.4175.5±43.9179.3±38.3174.5±46.4187.3±52.2168.7±40.0<0.001
HDL cholesterol (mg/dl)42.1±14.645.9±16.141.2±14.839.1±14.446.1±15.041.5±13.836.4±10.146.8±16.241.7±14.038.6±11.3<0.001
LDL cholesterol (mg/dl)100.3±37.694.7±34.499.3±37.6101.4±39.097.9±35.2102.2±38.2105.2±39.197.9±38.3109.7±38.497.0±36.1<0.001
Triglycerides (mg/dl)161.8±99.4121.9±62.9159.992.3200.6±120.3123.3±67.0174.8±107.9224.2±134.0149.9±103.3191.6±122.3240.1±102.1<0.001
Predialysis systolic BP (mmHg)136.4±19.5137.2±20.5134.8±20.4134.6±20.8139.3±18.4137.0±18.5137.5±19.2138.5±18.7138.7±18.0128.6±15.7<0.001
Serum sodium (mmol/L)137.9±3.4137.5±3.5137.7±3.5137.8±3.4138.1±3.5138.2±3.3138.2±3.3138.4±3.3138.3±3.3139.4±3.4<0.001
Body surface area (m2)1.8±0.21.6±0.21.8±0.22.0±0.21.6±0.21.8±0.22.1±0.21.7±0.21.8±0.22.1±0.3<0.001
FTI (kg/m2)9.8±4.55.1±1.510.6±3.419.6±4.24.7±1.710.2±9.320.2±3.93.9±1.910.5±3.222.8±4.3<0.001
LTI (kg/m2)12.5±3.111.4±1.910.7±2.310.0±2.614.4±2.413.6±2.513.6±2.418.4±3.017.7±3.218.3±3.0<0.001
Died (%)9±2917±4010±309±2810±307±257±2610±309±288±28
  • Values are mean baseline values±SDs. Median baseline values (interquartile range) are reported for CRP and dialysis vintage (25th–75th percentiles). Baseline was defined as the first BCM Body Composition Monitor measurement available for a patient in the study period (April 1, 2006–December 31, 2012), whereby all other values were averaged for the period ±30 days of the first BCM Body Composition Monitor measurement. P values were estimated with one-way ANOVA (standard with Gaussian assumption or Kruskal–Wallis test). BMI, body mass index; CRP, C-reactive protein; FTI, fat tissue index; LTI, lean tissue index.