Table 3.

Comparison of the estimated association of induction treatments on acute rejection at 1 year using multivariable logistic regression models

Multivariable ModelInduction TypeOR (95% CI)P Value
Steroid
 Logistic regression
IL-2 RA1
r-ATG0.80 (0.71 to 0.89)<0.001
No induction1.04 (0.92 to 1.16)0.55
 PS-weighted logistic regression
IL-2 RA1
r-ATG0.78 (0.70 to 0.88)<0.001
No induction0.96 (0.86 to 1.08)0.48
No Steroid
 Logistic regression
IL-2 RA1
r-ATG0.72 (0.58 to 0.90)0.004
Alemtuzumab0.52 (0.40 to 0.66)<0.001
 PS-weighted logistic regression
IL-2 RA1
r-ATG0.73 (0.59 to 0.90)0.004
Alemtuzumab0.53 (0.42 to 0.67)<0.001
  • Adjusted for donor factors (age, sex, and race), recipient factors (age, sex, race, cardiovascular morbidity, panel reactive antibody, retransplant status, and dialysis status) and transplant factors (donor/recipient weight ratio, HLA mismatch, and transplant year). PS, propensity score; IL2-RA, IL-2 receptor antagonist; r-ATG, rabbit anti-thymocyte globulin; OR, odds ratio; 95% CI, 95% confidence interval.